Evidence map›Paper›PMID 27408692›Full record

ReviewF1000Research2016

Chemotherapy-induced peripheral neuropathy: an update on the current understanding.

James Addington, Miriam Freimer

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in F1000Research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05873829 (The Effect of Hand-Foot Exercises on Platinum-Based Chemotheraphy Induced Peripheral Neuropathy Related Pain Severity, Falls and Quality of Life in Colorectal Cancer), which is not on this map. Cited by 64 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05873829 nacompletednot on this mapstarted 2022, after this paper: background citation

The Effect of Hand-Foot Exercises on Platinum-Based Chemotheraphy Induced Peripheral Neuropathy Related Pain Severity, Falls and Quality of Life in Colorectal Cancer

TypeinterventionalSponsorGulhane Training and Research HospitalRan2022 to 2022Enrolled39ConditionsChemotherapy-induced Peripheral Neuropathy, Colorectal CancerArmsHand-foot exercises
3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  6. Observational
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  15. The Potential Antinociceptive Effect and Mechanism ofMolecules (Basel, Switzerland) · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Antinociceptive Effect ofLife (Basel, Switzerland) · 2023
    Article
  20. Self-renewing macrophages in dorsal root ganglia contribute to promote nerve regeneration.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

James AddingtonDepartment of Neurology, The Ohio State University, Columbus, OH, USA.
Miriam FreimerDepartment of Neurology, The Ohio State University, Columbus, OH, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemotherapy-induced peripheral neuropathy is a common side effect of selected chemotherapeutic agents. Previous work has suggested that patients often under report the symptoms of chemotherapy-induced peripheral neuropathy and physicians fail to recognize the presence of such symptoms in a timely fashion. The precise pathophysiology that underlies chemotherapy-induced peripheral neuropathy, in both the acute and the chronic phase, remains complex and appears to be medication specific. Recent work has begun to demonstrate and further clarify potential pathophysiological processes that predispose and, ultimately, lead to the development of chemotherapy-induced peripheral neuropathy. There is increasing evidence that the pathway to neuropathy varies with each agent. With a clearer understanding of how these agents affect the peripheral nervous system, more targeted treatments can be developed in order to optimize treatment and prevent long-term side effects.

Indexed as

Chemotherapy-induced peripheral neuropathyCIPNperipheral neuropathyPlatinum agentsTaxanesVinca alkaloids

Identifiers

PMID27408692
PMCPMC4920214

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.