ArticleIndian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion2016
CD56 Negative Aggressive T Cell Large Granular Lymphocytic Leukemia.
Article in Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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6 citing papers in PubMed, 6 citations in OpenAlex.
- Aggressive T-large granular lymphocytic leukemia with an aberrant natural killer T-cell phenotype in an adult and derivation of a novel cell line.The Journal of international medical research · 2026Article
- A simplified prognostic score for T-cell large granular lymphocyte leukaemia.Annals of medicine · 2023Article
- Treatment for CD57-negative γδ T-cell large granular lymphocytic leukemia with pure red cell aplasia: A case report.World journal of clinical cases · 2021Article
- Complete remission of aggressive T-cell LGL leukemia with pentostatin therapy: first case report.Stem cell investigation · 2020Article
- [CD4(-)/CD8(-)/CD56(+)/TCRγδ(+) T-cell large granular lymphocyte leukemia presenting as aplastic anemia: a case report and literature review].Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi · 2019Article
- CD56-Negative Aggressive NK Cell Leukemia Relapsing as Multiple Cranial Nerve Palsies: Case Report and Literature Review.Case reports in hematology · 2017Article
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Authors and funding
5 authors at 1 institution in 1 country.
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Abstract
T cell large granular lymphocytic leukemia is a clonal proliferation of cytotoxic large granular T cells positive for CD3 and CD8. It is a chronic lymphoproliferative disorder with an indolent course. Therapeutic options include observation and low dose chemotherapy. Rarely, they have an aggressive course. Such cases have expression of NK cell associated antigens like CD56 in the T cells. These cases require more aggressive therapy with acute lymphoblastic leukemia regimens. We report a case of fatal CD56 negative T cell large granular lymphocytic leukemia in a 38 year old lady.
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