ArticleDevelopment (Cambridge, England)2016
An ancestral stomatal patterning module revealed in the non-vascular land plant Physcomitrella patens.
Article in Development (Cambridge, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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Who cites it
43 citing papers in PubMed, 66 citations in OpenAlex.
- Cell-based crop phenotyping for future climates.The New phytologist · 2026Review
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- Pan-genomic diversity of the EPF/EPFL gene family across wild and modern wheat species.BMC plant biology · 2026Article
- Regulation of stomatal development by receptor-like kinases and receptor-like proteins inFrontiers in plant science · 2026Review
- Nontoxic mesoporous silica nanoparticles protect Physcomitrium patens against salt stress.Stress biology · 2025Article
- Stomatal CO2 sensing in plants: control of gas exchange and interactions with environmental stimuli.Plant & cell physiology · 2025Review
- Comprehensive genome-wide identification and expression analysis of the EPF/EPFL gene family in oat.BMC genomics · 2025Article
- Pan-phylum genomes of hornworts reveal conserved autosomes but dynamic accessory and sex chromosomes.Nature plants · 2025Article
- Comprehensive identification of GASA genes in sunflower and expression profiling in response to drought.BMC genomics · 2024Article
- Comparative Genomics Analysis of the Populus Epidermal Pattern Factor (EPF) Family Revealed Their Regulatory Effects inInternational journal of molecular sciences · 2024Article
- Article
- Investigation on the Potential Functions of ZmEPF/EPFL Family Members in Response to Abiotic Stress in Maize.International journal of molecular sciences · 2024Article
- Genome-Wide Identification and Analysis of the EPF Gene Family inPlants (Basel, Switzerland) · 2023Article
- Article
- The K/HDEL receptor does not recycle but instead acts as a Golgi-gatekeeper.Nature communications · 2023Article
- Variations of stomata development in tea plant (Horticulture research · 2023Article
- Stu-miR827-TargetedInternational journal of molecular sciences · 2022Article
- Small EPIDERMAL PATTERNING FACTOR-LIKE2 peptides regulate awn development in rice.Plant physiology · 2022Article
- A Locus Controlling Leaf Rolling Degree in Wheat under Drought Stress Identified by Bulked Segregant Analysis.Plants (Basel, Switzerland) · 2022Article
- Pole position: How plant cells polarize along the axes.The Plant cell · 2022Review
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
The patterning of stomata plays a vital role in plant development and has emerged as a paradigm for the role of peptide signals in the spatial control of cellular differentiation. Research in Arabidopsis has identified a series of epidermal patterning factors (EPFs), which interact with an array of membrane-localised receptors and associated proteins (encoded by ERECTA and TMM genes) to control stomatal density and distribution. However, although it is well-established that stomata arose very early in the evolution of land plants, until now it has been unclear whether the established angiosperm stomatal patterning system represented by the EPF/TMM/ERECTA module reflects a conserved, universal mechanism in the plant kingdom. Here, we use molecular genetics to show that the moss Physcomitrella patens has conserved homologues of angiosperm EPF, TMM and at least one ERECTA gene that function together to permit the correct patterning of stomata and that, moreover, elements of the module retain function when transferred to Arabidopsis Our data characterise the stomatal patterning system in an evolutionarily distinct branch of plants and support the hypothesis that the EPF/TMM/ERECTA module represents an ancient patterning system.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.