Evidence map›Paper›PMID 27406405›Full record

ArticleScientific reports2016

Identification of an NDM-5-producing Escherichia coli Sequence Type 167 in a Neonatal Patient in China.

Yuan-Qi Zhu, Jing-Yi Zhao, Cha Xu, Hui Zhao, Nan Jia, Yan-Nian Li

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 73 citations in OpenAlex.

  1. Article
  2. Emergence of blaBMC microbiology · 2026
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  3. Dissemination of aFrontiers in microbiology · 2026
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  7. Resistome Study in Aquatic Environments.Journal of microbiology and biotechnology · 2023
    Review
  8. Article
  9. Article
  10. Article
  11. First identification ofJournal of medical microbiology · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Multiple NDM-5-ExpressingOpen forum infectious diseases · 2020
    Article
  17. Dissemination of themSphere · 2020
    Article
  18. Genotypic and Phenotypic Characterization ofFrontiers in microbiology · 2020
    Article
  19. Emergence of an NDM-5-ProducingInfection and drug resistance · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Yuan-Qi ZhuThe Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Qingdao 266003, China.
Jing-Yi ZhaoCenter for Bioengineering and Biotechnology, China University of Petroleum (East China), 66 Changjiang West Road, Qingdao 266580, China.
Cha XuMedical College, Qingdao University, 38 Dengzhou Road, Qingdao 266021, China.
Hui ZhaoMedical College, Qingdao University, 38 Dengzhou Road, Qingdao 266021, China.
Nan JiaMedical College, Qingdao University, 38 Dengzhou Road, Qingdao 266021, China.
Yan-Nian LiThe Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Qingdao 266003, China.
Qingdao University · CNAffiliated Hospital of Qingdao University · CNChina University of Petroleum, East China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emergence of New Delhi metallo-β-lactamase-producing Enterobacteriaceae has become a challenging threat to public health. Two carbapenem-resistant Escherichia coli, strain QD28 and QD29, were recovered from the aspirating sputum of a neonate and the urine of an adult in a Chinese hospital in 2013. Molecular typing revealed that both isolates belonged to the sequence type 167, but they were clonally diverse. Both isolates exhibited resistance to carbapenems, cephalosporins, ciprofloxacin, gentamicin, piperacillin-tazobactam and trimethoprim-sulfamethoxazole. In addition, strain QD28 was also resistant to aztreonam, and strain QD29 was resistant to amikacin, fosfomycin and minocycline. Antimicrobial resistance gene screening revealed that strain QD28 harbored aac(6')-Ib, blaCTX-M-14, blaNDM-5, blaTEM-1 and sul1 genes, and strain QD29 harbored aac(6')-Ib, blaCTX-M-3, blaNDM-5, blaTEM-1, rmtB, sul1 and sul2 genes. The blaNDM-5 gene was found to be located on a 46-kb plasmid in two isolates, and further sequence analysis showed that this plasmid was highly similar to the previously reported IncX3 plasmid pNDM-MGR194 in India. This is the first identification of blaNDM-5-carrying E. coli in the neonatal infection.

Indexed as

Anti-Bacterial Agentsbeta-LactamasesCarbapenem-Resistant EnterobacteriaceaeCarbapenemsChinaDrug Resistance, BacterialEnterobacteriaceae InfectionsHumansInfant, NewbornMicrobial Sensitivity TestsPlasmidsSputumAnti-Bacterial Agentsbeta lactamase NDM-5, E colibeta-LactamasesCarbapenems

Identifiers

PMID27406405
PMCPMC4942816
OpenAlexW2471856275

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.