Evidence map›Paper›PMID 27406142›Full record

ArticleEuropean journal of applied physiology2016

Ischaemic preconditioning does not alter the determinants of endurance running performance in the heat.

Carl A James, Ashley G B Willmott, Alan J Richardson, Peter W Watt, Neil S Maxwell

Abstract readControlled Clinical Trial
PubMed Publisher
In one paragraph

Article in European journal of applied physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. No influence of ischemic preconditioning on running economy.European journal of applied physiology · 2017
    Trial
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Carl A JamesEnvironmental Extremes Laboratory, Centre for Sport and Exercise Science and Medicine (SESAME), University of Brighton, Welkin Laboratories, Denton Road, Eastbourne, BN20 7SN, UK. carlos_james@hotmail.co.uk.
Ashley G B WillmottEnvironmental Extremes Laboratory, Centre for Sport and Exercise Science and Medicine (SESAME), University of Brighton, Welkin Laboratories, Denton Road, Eastbourne, BN20 7SN, UK.
Alan J RichardsonEnvironmental Extremes Laboratory, Centre for Sport and Exercise Science and Medicine (SESAME), University of Brighton, Welkin Laboratories, Denton Road, Eastbourne, BN20 7SN, UK.
Peter W WattEnvironmental Extremes Laboratory, Centre for Sport and Exercise Science and Medicine (SESAME), University of Brighton, Welkin Laboratories, Denton Road, Eastbourne, BN20 7SN, UK.
Neil S MaxwellEnvironmental Extremes Laboratory, Centre for Sport and Exercise Science and Medicine (SESAME), University of Brighton, Welkin Laboratories, Denton Road, Eastbourne, BN20 7SN, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIschaemic preconditioning (IP) has been shown to be ergogenic for endurance performance in normothermic conditions and alleviate physiological strain under hypoxia, potentially through haemodynamic and/or metabolic mechanisms. Exertional hyperthermia is characterised by competition for blood flow between the muscles and skin, an enhanced metabolic strain and impaired endurance performance. This study investigated the effect of IP on the determinants of endurance performance, through an incremental exercise test in the heat.

methodEleven males completed two graded exercise tests in the heat (32 °C, 62 % RH) until volitional exhaustion, preceded by IP (4 × 5 min 220 mmHg bilateral upper leg occlusion) or a control (CON) condition (4 × 5-min 50 mmHg bilateral).

resultIP did not improve running speeds at fixed blood lactate concentrations of 2 and 4 mMol L(-1) (p = 0.828), or affect blood glucose concentration throughout the trial [mean (±SD); CON 5.03 (0.94) mMol L(-1), IP 5.47 (1.38) mMol L(-1), p = 0.260). There was no difference in [Formula: see text]O2max [CON 55.5 (3.7) mL kg(-1) min(-1), IP 56.0 (2.6) mL kg(-1) min(-1), p = 0.436], average running economy [CON 222.3 (18.0) mL kg(-1) km(-1), IP 218.9 (16.5) mL kg(-1) km(-1), p = 0.125], or total running time during graded exercise [CON 347 (42) s, IP 379 (68) s, p = 0.166]. The IP procedure did not change muscle temperature [CON ∆ = 0.55 (0.57) °C, IP ∆ = 0.78 (0.85) °C, p = 0.568], but did reduce T CORE during exercise (~-0.1 °C, p = 0.001).

conclusionThe novel application of IP prior to exercise in the heat does not enhance the determinants of endurance performance. For events where IP appears ergogenic, muscle warming strategies are unnecessary as IP does not influence deep muscle temperature.

Indexed as

AcclimatizationAdultAthletic PerformanceBody Temperature RegulationHeat-Shock ResponseHot TemperatureHumansIschemic PreconditioningLactic AcidMaleOxygen ConsumptionPhysical EnduranceRunningLactic AcidEnduranceHyperthermiaIschaemic preconditioningLactate thresholdO2maxOcclusion

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.