Evidence map›Paper›PMID 27405996›Full record

ArticleBMC musculoskeletal disorders2016

Physical examination findings and their relationship with performance-based function in adults with knee osteoarthritis.

Maura D Iversen, Lori Lyn Price, Johan von Heideken, William F Harvey, Chenchen Wang

Open access · goldAbstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Does hallux valgus impair physical function?BMC musculoskeletal disorders · 2018
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 2 countries.

Maura D IversenDepartment of Physical Therapy, Movement and Rehabilitation Sciences, Northeastern University, 360 Huntington Avenue 301 C RB, Boston, MA, 02115, USA. m.iversen@neu.edu.
Lori Lyn PriceInstitute of Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, USA.
Johan von HeidekenDepartment of Physical Therapy, Movement and Rehabilitation Sciences, Northeastern University, 360 Huntington Avenue 301 C RB, Boston, MA, 02115, USA.
William F HarveyCenter for Integrative Medicine and Division of Rheumatology, Tufts Medical Center, Tufts University School of Medicine, Boston, MA, USA.
Chenchen WangCenter for Integrative Medicine and Division of Rheumatology, Tufts Medical Center, Tufts University School of Medicine, Boston, MA, USA.
Institute of Clinical Research · USKarolinska Institutet · SENortheastern University · USTufts Medical Center · USTufts University · US

Funding

Tufts Clinical and Translational Research InstituteUL1TR001064 · NCATS · TUFTS UNIVERSITY BOSTON · PI SELKER, HARRY P. · 2013 to 2017
$26.4M
TUFTS CLINICAL AND TRANSLATION SCIENCE INSTITUTE (UL1): BPCAUL1RR025752 · NCRR · TUFTS UNIVERSITY BOSTON · PI SELKER, HARRY P. · 2008 to 2011
$17.6M
Tufts Clinical and Translation Science Institute (UL1)UL1TR000073 · NCATS · TUFTS UNIVERSITY BOSTON · PI SELKER, HARRY P. · 2012 to 2013
$5.5M
Mentoring and Research in Patient-Oriented Integrative MedicineK24AT007323 · NCCIH · TUFTS MEDICAL CENTER · PI WANG, CHENCHEN · 2014 to 2023
$1.8M
NCATS NIH HHS UL1 TR000073NCATS NIH HHS UL1 TR001064NCCIH NIH HHS K24 AT007323NCRR NIH HHS UL1 RR025752
6 · The paper itself

Abstract

backgroundMany physical examination (PE) maneuvers exist to assess knee function, none of which are specific to knee osteoarthritis (KOA). The Osteoarthritis Research Society International also recommends the use of six functional performance measures to assess function in adults with KOA. While earlier studies have examined the relationship between PE findings and self-reported function or PE findings and select performance tests in adults with knee pain and KOA, few have examined the all three types of measures. This cross-sectional study specifically examines the relationships between results of PE findings, functional performance tests and self-reported function in adults with symptomatic KOA.

methodsWe used baseline PE data from a prospective randomized controlled trial in 87 participants aged ≥40 years with symptomatic and radiographic KOA. The PE performed by three experienced physical therapists included: muscle assessment, function and special tests. Participants also completed functional performance tests and the Western Ontario and McMaster Osteoarthritis Index (WOMAC). Multivariate linear regression identified contributions of PE findings towards functional performance and WOMAC scores, adjusting for age and gender.

resultsParticipants' mean age was 60.4 years (SD = 10.5), mean disease duration was 8.4 years (SD = 10.1) and 27 participants had varus knee alignment. Mean WOMAC pain and function scores were 211 (SD = 113) and 709 (SD = 394), respectively. Weakness was present in major hip and knee muscles. Seventy-nine participants had a positive Ely's, 65 a positive Waldron and 49 a positive Grind. Mean 6-min walk was 404 m (SD = 83) and mean Berg Balance was 53 (SD = 4). Regression analysis identified positive findings on 5 special tests (P < 0.05) as indicative of poorer 6 min walk. Positive Apley's was associated (P < 0.05) with slower 20 m walk and a positive Ober with poorer balance scores (P < 0.05).

conclusionsDiminished hip muscle strength and flexibility, and patella dysfunction were prevalent in these adults with symptomatic KOA. Results of functional performance tests suggest balance and walking ability are impaired and are associated with PE findings of muscle length imbalance, hip muscle weakness and patella dysfunction. None of the PE measures were associated with self-reported function. Therefore, performance-based test results may be more useful in informing rehabilitation interventions.

Indexed as

Muscle StrengthRange of Motion, ArticularAdultAgedAged, 80 and overCross-Sectional StudiesFemaleHipHumansKnee JointMaleMiddle AgedMuscle, SkeletalOsteoarthritis, KneePain MeasurementPhysical TherapistsKnee osteoarthritisPerformance-based functionPhysical examinationSelf-reported function

Identifiers

PMID27405996
PMCPMC4941016
OpenAlexW2464052985

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.