ArticleEvolution; international journal of organic evolution2016
Phylogenetic incongruence and the evolutionary origins of cardenolide-resistant forms of Na(+) ,K(+) -ATPase in Danaus butterflies.
Article in Evolution; international journal of organic evolution, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8 citing papers in PubMed.
- Toxin resistance in the monarch butterfly expanded its milkweed host range.bioRxiv : the preprint server for biology · 2026Article
- Selection Shapes the Genomic Landscape of Introgressed Ancestry in a Pair of Sympatric Sea Urchin Species.Genome biology and evolution · 2024Article
- Genome sequence of Ophryocystis elektroscirrha, an apicomplexan parasite of monarch butterflies: cryptic diversity and response to host-sequestered plant chemicals.BMC genomics · 2023Article
- Genomic evidence of speciation by fusion in a recent radiation of grasshoppers.Evolution; international journal of organic evolution · 2022Article
- Genomic evidence suggests further changes of butterfly names.The taxonomic report of the International Lepidoptera Survey · 2020Article
- Quinolizidine and Pyrrolizidine Alkaloid Chemical Ecology - a Mini-Review on Their Similarities and Differences.Journal of chemical ecology · 2019Review
- Plant Secondary Metabolites Modulate Insect Behavior-Steps Toward Addiction?Frontiers in physiology · 2018Review
- Mutational Biases Influence Parallel Adaptation.Molecular biology and evolution · 2017Article
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2 authors.
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Abstract
Many distantly related insect species are specialized feeders of cardenolide-containing host plants such as milkweed (Asclepias spp.). Previous studies have revealed frequent, parallel substitution of a functionally important amino acid substitution (N122H) in the alpha subunit of Na(+) ,K(+) -ATPase in a number of these species. This substitution facilitates the ability of these insects to feed on their toxic hosts and sequester cardenolides for their own use in defense. Among milkweed butterflies of the genus Danaus, the previously established phylogeny for this group suggests that N122H arose independently and fixed in two distinct lineages. We reevaluate this conclusion by examining Danaus phylogenetic relationships using >400 orthologous gene sequences assembled from transcriptome data. Our results indicate that the three Danaus species known to harbor the N122H substitution are more closely related than previously thought, consistent with a single, common origin for N122H. However, we also find evidence of both incomplete lineage sorting and post-speciation genetic exchange among these butterfly species, raising the possibility of collateral evolution of cardenolide-insensitivity in this species group.
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