Evidence map›Paper›PMID 27405522›Full record

Trial reportTrials2016

Mentalization-based treatment in groups for adolescents with borderline personality disorder (BPD) or subthreshold BPD versus treatment as usual (M-GAB): study protocol for a randomized controlled trial.

Emma Beck, Sune Bo, Matthias Gondan, Stig Poulsen, Liselotte Pedersen, Jesper Pedersen, Erik Simonsen

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Trials, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02068326 (Mentalization-Based Treatment in Groups for Adolescents With Borderline Personality Disorder), which is not on this map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02068326 nacompletednot on this map

Mentalization-Based Treatment in Groups for Adolescents With Borderline Personality Disorder (BPD) or Subthreshold BPD Versus Treatment As Usual - the M-GAB Randomized Controlled Trial

TypeinterventionalSponsorPsychiatric Research Unit, Region Zealand, DenmarkRan2015 to 2019Enrolled112ConditionsBorderline Personality DisorderArmsMentalization Based Treatment, Treatment As Usual
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Psychological therapies for people with borderline personality disorder.The Cochrane database of systematic reviews · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Emma BeckChild and Adolescent Psychiatric Department, Region Zealand, Smedegade 16, 4000, Roskilde, Denmark. ebk@regionsjaelland.dk.ORCID 0000-0002-4711-5417
Sune BoChild and Adolescent Psychiatric Department, Region Zealand, Smedegade 16, 4000, Roskilde, Denmark.
Matthias GondanDepartment of Psychology, University of Copenhagen, Øster Farimagsgade 2A, 1353, Copenhagen K, Denmark.
Stig PoulsenDepartment of Psychology, University of Copenhagen, Øster Farimagsgade 2A, 1353, Copenhagen K, Denmark.
Liselotte PedersenPsychiatric Research Unit, Region Zealand, Fælledvej 6, 4200, Slagelse, Denmark.
Jesper PedersenChild and Adolescent Psychiatric Department, Region Zealand, Smedegade 16, 4000, Roskilde, Denmark.
Erik SimonsenPsychiatric Research Unit, Region Zealand, Fælledvej 6, 4200, Slagelse, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEvidence-based outpatient psychotherapeutic programs are first-line treatment of borderline personality disorder (BPD). Early and effective treatment of BPD is crucial to the prevention of its individual, psychosocial, and economic consequences. However, in spite of recent advantages in diagnosing adolescent BPD, there is a lack of cost-effective evidence-based treatment programs for adolescents. Mentalization-based treatment is an evidence-based program for BPD, originally developed for adults. METHODS/

designAIMS/HYPOTHESES: We will investigate whether a specifically designed mentalization-based treatment in groups is an efficacious treatment for adolescents with BPD or subthreshold BPD compared to treatment as usual. The trial is a four-center, two-armed, parallel-group, assessor-blinded randomized clinical superiority trial. One hundred twelve patients aged 14 to 17 referred to Child and Adolescent Psychiatric Clinics in Region Zealand are randomized to 1 year of either mentalization-based treatment in groups or treatment as usual. Patients will be included if they meet at least four DSM-5 criteria for BPD. The primary outcome is self-reported borderline features at discharge. Secondary outcomes will include self-harm, depression, BPD criteria, externalizing and internalizing symptoms, and social functioning, together with parental reports on borderline features, externalizing and internalizing symptoms. Measures of attachment and mentalization will be included as mediational variables. Follow-up assessment will take place at 3 and 12 months after end of treatment. DISCUSSION: This is the first randomized controlled trial to test the efficacy of a group-based mentalization-based treatment for adolescents with BPD or subthreshold BPD. If the results confirm our hypothesis, this trial will add to the treatment options of cost-effective treatment of adolescent BPD.

trial registrationClinicaltrials.gov NCT02068326 , February 19, 2014.

Indexed as

Adolescent BehaviorPersonalityTheory of MindAdolescentAge FactorsBorderline Personality DisorderClinical ProtocolsDenmarkFemaleHumansMalePsychiatric Status Rating ScalesPsychotherapy, GroupResearch DesignTime FactorsTreatment OutcomeAdolescenceBorderline personality disorderGroup psychotherapyMentalization-based treatmentMentalizing

Identifiers

PMID27405522
PMCPMC4942923

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.