Evidence map›Paper›PMID 27405478›Full record

ArticleSurgical endoscopy2017

The effects of bariatric surgeries on nonalcoholic fatty liver disease.

Tamadar Aldoheyan, Mazen Hassanain, Amnah Al-Mulhim, Atheer Al-Sabhan, Shaden Al-Amro, Fahad Bamehriz, Hisham Al-Khalidi

Abstract read
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 4 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 4 syntheses or guidelines pooled it, 44 citations in OpenAlex.

  1. Pooled it
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  4. Pooled it
  5. Article
  6. Article
  7. Current strategies for nonalcoholic fatty liver disease treatment (Review).International journal of molecular medicine · 2024
    Review
  8. Article
  9. Foregut bypassHepatobiliary surgery and nutrition · 2023
    Article
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  11. Review
  12. Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Tamadar AldoheyanDepartment of Surgery, College of Medicine, King Saud University, Riyadh, Saudi Arabia.ORCID 0000-0002-6425-6676
Mazen HassanainDepartment of Surgery, College of Medicine, King Saud University, Riyadh, Saudi Arabia. mhassanain@ksu.edu.sa.
Amnah Al-MulhimDepartment of Surgery, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Atheer Al-SabhanDepartment of Surgery, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Shaden Al-AmroDepartment of Surgery, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Fahad BamehrizDepartment of Surgery, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Hisham Al-KhalidiDepartment of Pathology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
King Saud University · SAEmory University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and is associated with obesity. Bariatric surgery has been shown to be the most effective method for weight reduction. However, no conclusive data exists on the effects of weight reduction surgery on NAFLD. This study aimed to characterize liver histology, metabolic status, and liver function changes in patients who underwent bariatric surgery, before and after the weight-reduction procedure. This is a phase 1 report of a prospective cohort study of patients who underwent bariatric surgery. Biopsies were obtained at baseline (intraoperatively) and 3 months postoperatively. Clinical characteristics, biochemical profile, and histopathological data [steatosis, NAFLD activity score (NAS), hepatocyte ballooning, lobular inflammation, and degree of fibrosis] were obtained at each time point. Twenty-seven patients were included (9 men and 18 women), and the median age was 35 ± 8 years old. At baseline, 3 patients had dyslipidemia, 4 had diabetes, and 5 patients had hypertension, which did not change at follow-up. The average body mass index decreased from 44.6 ± 7.8 to 34.2 ± 6.3 kg/m

Indexed as

Bariatric SurgeryAdultBiopsyCohort StudiesFemaleHepatocytesHumansLiverMaleNon-alcoholic Fatty Liver DiseaseObesity, MorbidBariatricGastric bandingGastric bypassInsulin resistance biliopancreatic diversion with duodenal switchNonalcoholic fatty liver diseaseObesitySleeve gastrectomySteatosis

Identifiers

PMID27405478
OpenAlexW2466141210

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.