ArticleAnnals of the American Thoracic Society2016
Mortality Trends of Acute Respiratory Distress Syndrome in the United States from 1999 to 2013.
Article in Annals of the American Thoracic Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers.
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Who cites it
92 citing papers in PubMed, 149 citations in OpenAlex.
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- Trends and disparities in acute respiratory distress syndrome-related mortality in the United States, 1999-2020: a CDC WONDER database analysis.Annals of medicine and surgery (2012) · 2026Article
- Trends and mortality due to acute respiratory distress syndrome in the United States (1999-2023): A 25-year nationwide study.Medicine · 2026Article
- Needs of Acute Respiratory Failure Survivors Throughout 1 Year of Recovery: A Qualitative Analysis Using the Timing It Right Framework.CHEST critical care · 2025Article
- Aging and lung diseases: Unraveling mechanisms and therapeutic targets.Chinese medical journal pulmonary and critical care medicine · 2025Review
- Empirical phenotyping of joint patient-care data supports hypothesis-driven investigation of mechanical ventilation consequences.Scientific reports · 2025Article
- The predictive value of respiration parameters and the Glasgow Goma score for mortality of sepsis patients with acute respiratory distress syndrome: Insights from the MIMIC-IV database.Pakistan journal of medical sciences · 2025Article
- Two Physiologic Latent Classes of Acute Hypoxemic Respiratory Failure in Sepsis Are Distinguished by Lung Mechanics and Gas Exchange.Critical care explorations · 2025Article
- High-fat diet obesity exacerbates acute lung injury-induced dysregulation of fatty acid oxidation in alveolar epithelial type 2 cells.American journal of physiology. Lung cellular and molecular physiology · 2025Article
- Article
- Epidemiological trends of mechanically ventilated acute respiratory distress syndrome in the twenty-first century: a nationwide, population-based retrospective study.Journal of intensive care · 2025Article
- Acute respiratory distress syndrome (ARDS): from mechanistic insights to therapeutic strategies.MedComm · 2025Review
- Molecular signatures of alveolar type II cell differentiation in acute respiratory distress syndrome.Frontiers in medicine · 2025Article
- Race and Ethnicity Disparities in Management and Outcomes of Critically Ill Adults with Acute Respiratory Failure.Critical care clinics · 2024Review
- Metabolic syndrome is associated with mortality in elderly patients with acute respiratory distress syndrome.Diabetology & metabolic syndrome · 2024Article
- Article
- Broussonin E against acute respiratory distress syndrome: the potential roles of anti-inflammatory.Naunyn-Schmiedeberg's archives of pharmacology · 2024Article
- Outcomes of Acute Respiratory Failure in Patients With Cancer in the United States.Mayo Clinic proceedings · 2024Review
- Lower body mass index is an independent predictor of mortality in older patients with acute respiratory distress syndrome.Heliyon · 2024Article
32 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
rationaleAcute respiratory distress syndrome (ARDS) is an acute hypoxemic respiratory failure seen in critically ill patients after an inciting injury. The burden of ARDS mortality in the United States in recent years is not well characterized.
objectivesIn this study, we aimed to describe trends in the annual incidence of ARDS mortality in the United States from 1999 to 2013. We also describe demographic characteristics, geographic and seasonal trends, and other associated underlying causes of death in this population.
methodsData on all deceased U.S. residents are available through the Multiple Cause of Death (MCOD) database of the National Center for Health Statistics. ARDS-related deaths were identified in the MCOD database using International Classification of Diseases, 10th Revision. MEASUREMENTS AND MAIN
resultsAggregate annual crude and age-adjusted mortality rates and mortality rate ratios were used to compare various demographic subpopulations. Over the 15-year period, the national ARDS-related age-adjusted mortality rate demonstrated an annual seasonal variation, peaking in winter. The annual rate decreased in a nonlinear fashion, with a plateau from 2010 to 2013. The ARDS-related age-adjusted mortality rate was 5.01 per 100,000 persons (95% confidence interval, 4.92-5.09) in 1999 and 2.82 per 100,000 persons (95% confidence interval, 2.76-2.88) in 2013. Males had a higher average ARDS-related mortality rate than did females. Asian/Pacific Islanders had the lowest average age-adjusted ARDS-related mortality rate, and black/African-American individuals, the highest.
conclusionsNational age-adjusted ARDS-related mortality rates decreased between 1999 and 2013 in the United States, yet still show relative racial and sex disparities. However, death certificates largely underestimate the overall mortality burden from ARDS when compared with studies of clinically ascertained cases.
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