Evidence map›Paper›PMID 27403414›Full record

ReviewGastrointestinal tumors2016

Nutrition in Pancreatic Cancer: A Review.

Simone Gärtner, Janine Krüger, Ali A Aghdassi, Antje Steveling, Peter Simon, Markus M Lerch, Julia Mayerle

Registry-linked trialAbstract readReview
In one paragraph

Review in Gastrointestinal tumors, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03245658 (The Effect of Medical Cannabis Inpatients With Palliative Pancreatic Cancer), which is not on this map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03245658 phase2withdrawnnot on this mapstarted 2017, after this paper: background citation

The Effect of Medical Cannabis Inpatients With Palliative Pancreatic Cancer

TypeinterventionalSponsorJens Rikardt AndersenRan2017 to 2018Enrolled0ConditionsNeoplasms Pancreatic, Cachexia, Cancer, CannabisArmsTHC and CBD Mixture
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Treatment of pancreatic insufficiency using pancreatic extract in patients with advanced pancreatic cancer: a pilot study (PICNIC).Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2017
    Trial
  5. Article
  6. Comparing efficacy of a jejunostomy tubeWorld journal of gastrointestinal surgery · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Observational
  13. Review
  14. Driver Mutations of Pancreatic Cancer Affect CaFunction (Oxford, England) · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Impact of Preoperative Malnutrition on Postoperative Long-Term Outcomes of Patients With Pancreatic Head Cancer.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Simone GärtnerDepartment of Medicine A, University Medicine Greifswald, Greifswald, Germany.
Janine KrügerDepartment of Medicine A, University Medicine Greifswald, Greifswald, Germany.
Ali A AghdassiDepartment of Medicine A, University Medicine Greifswald, Greifswald, Germany.
Antje StevelingDepartment of Medicine A, University Medicine Greifswald, Greifswald, Germany.
Peter SimonDepartment of Medicine A, University Medicine Greifswald, Greifswald, Germany.
Markus M LerchDepartment of Medicine A, University Medicine Greifswald, Greifswald, Germany.
Julia MayerleDepartment of Medicine A, University Medicine Greifswald, Greifswald, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPancreatic cancer is the fourth leading cause of cancer-related mortality in both genders. More than 80% of patients suffer from significant weight loss at diagnosis and over time develop severe cachexia. Early nutritional support is therefore essential. SUMMARY: This review evaluates the different nutritional therapies, such as enteral nutrition, parenteral nutrition and special nutritional supplements, on nutritional status, quality of life and survival. KEY MESSAGE: Due to the high prevalence of malnutrition and the rapid development of anorexia-cachexia-syndrome, early nutritional intervention is crucial and supported by clinical data. PRACTICAL IMPLICATIONS: Enteral nutrition should be preferred over parenteral nutrition. Omega-3 fatty acids and l-carnitine are promising substances for the prevention of severe cachexia, but further randomized controlled trials are needed to establish generally accepted guidelines on nutrition in pancreatic cancer.

Indexed as

Enteral nutritionL-CarnitineOmega-3 fatty acidsPancreatic cancerParenteral nutrition

Identifiers

PMID27403414
PMCPMC4924449

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.