ArticleNeural plasticity2016
Exploiting Interlimb Arm and Leg Connections for Walking Rehabilitation: A Training Intervention in Stroke.
Article in Neural plasticity, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 41 citations in OpenAlex.
- Do Leg-Focused Exercises Improve Arm and Hand Function for Individuals With Neurologic Disorders? A Scoping Review.Archives of rehabilitation research and clinical translation · 2026Review
- Bidirectional modulation of soleus spinal excitability induced by upper limb movement practice.Experimental brain research · 2026Article
- Assessment of the influence of lower limb cycling on arm muscle coordination during upper limb cycling: a pilot study.Journal of neuroengineering and rehabilitation · 2026Article
- Pushing the Limits of Interlimb Connectivity: Neuromodulation and Beyond.Biomedicines · 2025Review
- Measuring Neuroplasticity in Response to Cardiovascular Exercise in People With Stroke: A Critical Perspective.Neurorehabilitation and neural repair · 2024Article
- Five weeks of Yuishinkai karate training improves balance and neuromuscular function in older adults: a preliminary study.BMC sports science, medicine & rehabilitation · 2022Article
- Neural Substrates of Transcutaneous Spinal Cord Stimulation: Neuromodulation across Multiple Segments of the Spinal Cord.Journal of clinical medicine · 2022Review
- Step-to-step variability indicates disruption to balance control when linking the arms and legs during treadmill walking.PloS one · 2022Article
- A protocol to analyze the global literature on the clinical benefit of interlimb-coordinated intervention in gait recovery and the associated neurophysiological changes in patients with stroke.Frontiers in neurology · 2022Article
- Using a simple rope-pulley system that mechanically couples the arms, legs, and treadmill reduces the metabolic cost of walking.Journal of neuroengineering and rehabilitation · 2021Article
- Ipsilateral motor pathways to the lower limb after stroke: Insights and opportunities.Journal of neuroscience research · 2021Review
- Simultaneous Cervical and Lumbar Spinal Cord Stimulation Induces Facilitation of Both Spinal and Corticospinal Circuitry in Humans.Frontiers in neuroscience · 2021Article
- Preliminary development and technical evaluation of a belt-actuated robotic rehabilitation platform.Technology and health care : official journal of the European Society for Engineering and Medicine · 2021Article
- Robot controlled, continuous passive movement of the ankle reduces spinal cord excitability in participants with spasticity: a pilot study.Experimental brain research · 2019Article
- Training-Induced Neural Plasticity and Strength Are Amplified After Stroke.Exercise and sport sciences reviews · 2019Review
- Exploiting cervicolumbar connections enhances short-term spinal cord plasticity induced by rhythmic movement.Experimental brain research · 2019Article
- Sherlock Holmes and the curious case of the human locomotor central pattern generator.Journal of neurophysiology · 2018Review
- Unilateral wrist extension training after stroke improves strength and neural plasticity in both arms.Experimental brain research · 2018Article
- Rhythmic arm cycling training improves walking and neurophysiological integrity in chronic stroke: the arms can give legs a helping hand in rehabilitation.Journal of neurophysiology · 2018Article
- Long-Term Plasticity in Reflex Excitability Induced by Five Weeks of Arm and Leg Cycling Training after Stroke.Brain sciences · 2016Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rhythmic arm and leg (A&L) movements share common elements of neural control. The extent to which A&L cycling training can lead to training adaptations which transfer to improved walking function remains untested. The purpose of this study was to test the efficacy of A&L cycling training as a modality to improve locomotor function after stroke. Nineteen chronic stroke (>six months) participants were recruited and performed 30 minutes of A&L cycling training three times a week for five weeks. Changes in walking function were assessed with (1) clinical tests; (2) strength during isometric contractions; and (3) treadmill walking performance and cutaneous reflex modulation. A multiple baseline (3 pretests) within-subject control design was used. Data show that A&L cycling training improved clinical walking status increased strength by ~25%, improved modulation of muscle activity by ~25%, increased range of motion by ~20%, decreased stride duration, increased frequency, and improved modulation of cutaneous reflexes during treadmill walking. On most variables, the majority of participants showed a significant improvement in walking ability. These results suggest that exploiting arm and leg connections with A&L cycling training, an accessible and cost-effective training modality, could be used to improve walking ability after stroke.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.