ArticleBMJ open diabetes research & care2016
Physical activity, sedentary behaviors and the incidence of type 2 diabetes mellitus: the Multi-Ethnic Study of Atherosclerosis (MESA).
Article in BMJ open diabetes research & care, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 4 of them syntheses that pooled it.
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Who cites it
64 citing papers in PubMed, 4 syntheses or guidelines pooled it, 146 citations in OpenAlex.
- Impact of COVID-19 pandemic lockdown on movement behaviours of children and adolescents: a systematic review.BMJ global health · 2022Pooled it
- Secondary analyses of global datasets: do obesity and physical activity explain variation in diabetes risk across populations?International journal of obesity (2005) · 2021Pooled it
- Chronic obstructive pulmonary disease, lung function and risk of type 2 diabetes: a systematic review and meta-analysis of cohort studies.BMC pulmonary medicine · 2020Pooled it
- Sedentary behaviour and risk of all-cause, cardiovascular and cancer mortality, and incident type 2 diabetes: a systematic review and dose response meta-analysis.European journal of epidemiology · 2018Pooled it
- Effects of interrupting daily sedentary behavior on children's glucose metabolism: A 6-day randomized controlled trial.Pediatric diabetes · 2022Trial
- Modelling the potential health and economic benefits of reducing population sitting time in Australia.The international journal of behavioral nutrition and physical activity · 2022Trial
- The Effects of Aerobic-Resistance Training and Broccoli Supplementation on Plasma Dectin-1 and Insulin Resistance in Males with Type 2 Diabetes.Nutrients · 2021Trial
- Resistance exercise breaks during prolonged sitting augment the blood flow response to a subsequent oral glucose load in sedentary adults.Experimental physiology · 2026Article
- Sedentary Behavior, Physical Activity, and Hypertension: Genetic Liability and the Role of Metabolic Factors.Clinical cardiology · 2026Article
- Risk of Type 2 Diabetes According to Body Mass Index, Television Viewing Time, and Their Combination in the Japanese Population: Findings From the Japan Collaborative Cohort Study.Journal of obesity · 2026Article
- Long Non-Coding RNAs in Diabetic Cardiomyopathy: Potential Function as Biomarkers and Therapeutic Targets of Exercise Training.Journal of cardiovascular translational research · 2025Review
- Racial Disparities of Type 2 Diabetes Through Exercise: The Multi-Ethnic Study of Atherosclerosis.American journal of preventive medicine · 2025Article
- Effects of Age and Sex on Systemic Inflammation and Cardiometabolic Function in Individuals With Type 2 Diabetes.Journal of the American Heart Association · 2025Article
- Antidiabetic Activity ofJournal of experimental pharmacology · 2025Article
- Insulin resistance and its association with coronary heart disease: insights from bioinformatics analysis.Frontiers in endocrinology · 2025Article
- Relationship of Plasma Apolipoprotein C-I Truncation With Risk of Diabetes in the Multi-Ethnic Study of Atherosclerosis and the Actos Now for the Prevention of Diabetes Study.Diabetes care · 2024Article
- Association of dietary and lifestyle inflammatory indices with type 2 diabetes risk in Iranian adults.BMC endocrine disorders · 2024Article
- Factors associated with physical inactivity among Palestinians with type 2 diabetes mellitus treated in resource-limited settings.Scientific reports · 2024Article
- COPD and T2DM: a Mendelian randomization study.Frontiers in endocrinology · 2024Article
- Intervening to reduce sedentary behavior among African American elders: the "Stand Up and Move More" intervention.Health promotion perspectives · 2024Article
4 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
11 authors at 6 institutions in 1 country.
Funding
Abstract
backgroundThe association between physical activity (PA), sedentary behavior, and incident diabetes has been assessed in whites but is less well investigated in multiethnic populations.
objectiveTo assess the association between PA, sedentary behavior, and incident diabetes in the Multi-Ethnic Study of Atherosclerosis. RESEARCH DESIGN AND
methodsIncident diabetes was assessed among adults without prevalent baseline diabetes (2000-2002) at 5 in-person examinations between 2002 and 2012. Baseline PA (moderate, vigorous, and exercise-specific; metabolic equivalents of task-hours/week) and sedentary behaviors (television watching, reading; hours/day) were assessed by questionnaire. HRs were estimated using Cox proportional hazard models.
resultsAmong 5829 adults (mean age 61.8 years, 54% female, 42% white, 12% Chinese-American, 26% African-American, 21% Hispanic-American), there were 655 incident diabetes cases (median follow-up 11.1 years). After adjustment, diabetes risk was lower in those with brisk or striding compared with none or casual walking pace (HR 0.67; 95% CI 0.54 to 0.84), higher levels of exercise PA (HR for highest vs lowest quartile 0.79; 95% CI 0.63 to 0.98), and any compared with no vigorous PA (HR 0.79; 95% CI 0.66 to 0.95). Race/ethnicity influenced the association of walking pace, exercise PA, and any vigorous PA on diabetes risk, which was only significant among whites. Total leisure sedentary behaviors (HR for highest vs lowest quartile 1.65; 95% CI 1.26 to 2.14) and television watching (HR for highest vs lowest quartile 2.68; 95% CI 1.38 to 5.21) were significantly associated with diabetes risk in multiethnic analyses and were influenced by race/ethnicity.
conclusionsThese results confirm the importance of PA and sedentary behavior on diabetes risk in a multiethnic population and demonstrate potential variations across race/ethnic groups.
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