Evidence map›Paper›PMID 27403306›Full record

ArticleUnited European gastroenterology journal2016

Gastric malt lymphoma: Analysis of a series of consecutive patients over 20 years.

Joana Moleiro, Sara Ferreira, Pedro Lage, A Dias Pereira

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in United European gastroenterology journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Effectiveness ofWorld journal of gastroenterology · 2023
    Pooled it
  3. Review
  4. Article
  5. Review
  6. Five-year Progress of Gastric MALT Lymphoma Presenting as Gastric Outlet Obstruction.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2023
    Article
  7. Article
  8. Role of the gut microbiota in hematologic cancer.Frontiers in microbiology · 2023
    Review
  9. Review
  10. Radiotherapy for gastric mucosa-associated lymphoid tissue lymphoma.World journal of gastrointestinal oncology · 2021
    Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Population screening and treatment of Helicobacter pylori infection.Nature reviews. Gastroenterology & hepatology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Joana MoleiroGastroenterology Department, Instituto Português de Oncologia de Lisboa, Portugal.
Sara FerreiraGastroenterology Department, Instituto Português de Oncologia de Lisboa, Portugal.
Pedro LageGastroenterology Department, Instituto Português de Oncologia de Lisboa, Portugal.
A Dias PereiraGastroenterology Department, Instituto Português de Oncologia de Lisboa, Portugal.
IPO Porto · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

INTRODUCTION AND

aimsGastric mucosa-associated lymphoid tissue (MALT) lymphoma is closely associated with Helicobacter pylori (HP) infection. Our aim was to evaluate demographic, clinical and endoscopic characteristics of gastric MALT lymphoma patients, as well as to analyse response to treatment and factors that affect complete remission (CR) and relapse. We also assessed the long-term prognosis.

methodsThe study involved a retrospective evaluation of consecutive patients admitted with gastric MALT lymphoma (1993-2013).

resultsA total of 144 patients (76 men; mean age 56) were included. At stage EI, 94/103 patients (92%) received HP eradication and 78 (83%) achieved CR after a mean period of 7 months (2-63 months) and 67 (86%) remained in CR after a mean follow-up time of 105 months. HP infection status (p = 0.004) and lymphoma localisation to the antrum plus body (p = 0.016) were associated with higher and lower CR rates, respectively. Relapse occurred in 11/78 (14%) patients after a mean period of 21 months. The absence of HP re-infection (p = 0.038), the need of only one eradication regimen (p = 0.009) and antrum lymphomas (p = 0.031) correlated with lower relapse rates. At stage EII, HP eradication was performed in 17/24 patients but only five experienced CR (30%). Among 16 patients diagnosed at stage EIV, nine achieved CR after chemotherapy ± surgery and 3/7 without remission died due to disease progression. The 5- and 10-year overall disease free survival rates were 90.5% and 79.1%, respectively.

conclusionsMost patients were diagnosed at an early stage. Eradication therapy was highly effective in inducing complete remission. Long-term evaluation showed that the long-term prognosis was very favourable.

Indexed as

complete remissioneradication therapyGastric mucosa-associated lymphoid tissue lymphomaHelicobacter pylorilong-term prognosis

Identifiers

PMID27403306
PMCPMC4924435
OpenAlexW2266971872

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.