ArticleUnited European gastroenterology journal2016
Real-time diagnosis of H. pylori infection during endoscopy: Accuracy of an innovative tool (EndoFaster).
Article in United European gastroenterology journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Validation of a Gastric-Juice-Analysis-Based Approach toDiagnostics (Basel, Switzerland) · 2026Article
- Endoscopic appearances of gastric mucosa in different endoscopic models according to H. pylori infection status.JGH open : an open access journal of gastroenterology and hepatology · 2024Review
- Can Gastric Juice Analysis with EndoFasterHealthcare (Basel, Switzerland) · 2023Article
- Intraprocedural gastric juice analysis as compared to rapid urease test for real-time detection ofWorld journal of gastroenterology · 2023Article
- Endoscopic Diagnosis for H. pylori Infection: White Light Imaging (WLI) vs. Image-Enhanced Endoscopy (IEE).Asian Pacific journal of cancer prevention : APJCP · 2021Article
- Diagnostic Accuracy of EndoFaster® and Narrow-Band Imaging Endoscopy in Patients with Impaired Gastric Acid Secretion: A Real-Time Prospective Study.Gastroenterology research and practice · 2021Article
- Pathogenesis and clinical management ofWorld journal of gastroenterology · 2019Review
- Diagnostic approach toAnnals of gastroenterologyReview
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEndoFaster is novel device able to perform real-time ammonium measurement in gastric juice allowing H. pylori diagnosis during endoscopy. This large study aimed to validate the accuracy of EndoFaster for real-time H. pylori detection.
methodsConsecutive patients who underwent upper endoscopy in two centres were prospectively enrolled. During endoscopy, 4 ml of gastric juice were aspirated to perform automatic analysis by EndoFaster within 90 seconds, and H. pylori was considered present (>62 ppm/ml) or absent (≤62 ppm/ml). Accuracy was measured by using histology as gold standard, and (13)C-urea breath test (UBT) in discordant cases. Accuracy, sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) were calculated.
resultsOverall, 189 patients were enrolled, but in seven (3.4%) the aspirated gastric juice amount was insufficient to perform the test. The accuracy, sensitivity, specificity, PPV, and NPV were 87.4%, 90.3%, 85.5%, 80.2%, 93.1%, respectively, and 92.6%, 97.1%, 89.7%, 85.9%, 98.0%, respectively, when H. pylori status was reclassified according to the UBT result in discordant cases.
conclusionsThis study found a high accuracy/feasibility of EndoFaster for real-time H. pylori diagnosis. Use of EndoFaster may allow selecting those patients in whom routine gastric biopsies could be avoided.
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