Evidence map›Paper›PMID 27403225›Full record

ArticleJournal of vascular and interventional neurology2016

Multiparametric Approach Enhances Detection of Patients with Cerebral TIAs at Risk of Stroke: A Prospective Pilot Case Series.

Foad Abd-Allah, Tarek Zoheir Tawfik, Reham Mohammed Shamloul, Montasser M Hegazy, Assem Hashad, Ayman Ismail Kamel, Dina Farees, Nevin M Shalaby

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In one paragraph

Article in Journal of vascular and interventional neurology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Foad Abd-AllahDepartment of Neurology, Cairo University, Cairo, Egypt.
Tarek Zoheir TawfikDepartment of Neurology, Cairo University, Cairo, Egypt.
Reham Mohammed ShamloulDepartment of Neurology, Cairo University, Cairo, Egypt.
Montasser M HegazyDepartment of Neurology, Cairo University, Cairo, Egypt.
Assem HashadDepartment of Cardiology, Cairo University, Cairo, Egypt.
Ayman Ismail KamelDepartment of Radiology, Cairo University, Cairo, Egypt.
Dina FareesDepartment of Neurology, Cairo University, Cairo, Egypt.
Nevin M ShalabyDepartment of Neurology, Cairo University, Cairo, Egypt.
Cairo University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with transient ischemic attack (TIA) are generally clinically unstable, with fear of developing a handicapping stroke. Identification of those at highest and lowest risk of stroke in the first days and weeks after a TIA would allow appropriate use of worthy secondary prevention strategies.

objectiveIncorporation of a clinical scoring system, neurovascular imaging, and magnetic resonance-diffusion-weighted imaging (MR-DWI) to help predicting risk of developing an ischemic stroke following a TIA. SUBJECTS AND

methodsA prospective observational study was conducted on 25 patients with TIAs, 64% were females, and 26% were males, with a mean age of 57±10.36. Patients were assessed clinically and an ABCD(2) score was applied. Patients have undergone diffusion-weighted imaging (DWI), within 24 h from the event, and intra- and extracranial duplex study. Patients were followed up at intervals of one week, three months, six months, and one year.

resultsSix patients (24%) developed stroke on their follow-up, most of them (83.3%) had their strokes within the first three months and had an initial ABCD(2) score of ≥4. The development of stroke was associated with the presence of significant extra and/or intracranial vessel disease (P=0.006) and the presence of acute lesions on their DWI (P=0.035).

conclusionIncorporation of brain MR-DWIs and neurovascular imaging together with the ABCD(2) score improves prediction of ischemic stroke following TIA.

Indexed as

ABCD2 scorediffusion weighted image (DWI)neurovascular imagingstroke risktransient ischemic attack

Identifiers

PMID27403225
PMCPMC4925755
OpenAlexW2477453791

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.