ArticleObstetrics and gynecology international2016
Pregnancy in Sickle Cell Disease Is a Very High-Risk Situation: An Observational Study.
Article in Obstetrics and gynecology international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.
- Pregnancy in the Sickle Cell Disease and Fetomaternal Outcomes in Different Sickle cell Genotypes: A Systematic Review and Meta-Analysis.Ethiopian journal of health sciences · 2022Pooled it
- Clinical Implications of Sickle Cell Thalassemia on Pregnancy Outcomes: A Systematic Review.Diagnostics (Basel, Switzerland) · 2026Review
- Maternal and perinatal outcomes of sickle cell disease in pregnancy: A nationwide study in France.British journal of haematology · 2025Article
- PREGNANCY OUTCOMES IN WOMEN WITH SICKLE CELL DISEASE AT A TERTIARY HOSPITAL IN NIGERIA: A FIVE-YEAR RETROSPECTIVE STUDY.Annals of Ibadan postgraduate medicine · 2024Article
- Sickle cell anemia and pregnancy: Profile of hemodynamic changes in sickle cell pregnant women in Kinshasa.EJHaem · 2023Article
- Outcomes of Pregnancy in Sickle Cell Disease Patients: Results from the Prospective ESCORT-HU Cohort Study.Biomedicines · 2023Article
- Hypertensive emergency versus preeclampsia in a patient with sickle cell disease: a case report.World journal of emergency medicine · 2023Article
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- Ecological analysis of demographic-, nutritional- and housing-related factors associated with anaemia among women of reproductive age group in Nigeria.Journal of health, population, and nutrition · 2022Article
- "Is the health system ready?" A qualitative exploration of stakeholders' opinions about the feasibility of preconception care services in the Nigerian health system.Reproductive health · 2022Article
- Main Complications during Pregnancy and Recommendations for Adequate Antenatal Care in Sickle Cell Disease: A Literature Review.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2022Review
- Maternal hereditary hemolytic anemia and birth defects in the National Birth Defects Prevention Study.Birth defects research · 2022Article
- Evaluation of Stillbirth Among Pregnant People With Sickle Cell Trait.JAMA network open · 2021Article
- Pregnancies and Neonatal Outcomes in Patients with Sickle Cell Disease (SCD): Still a (High-)Risk Constellation?Journal of personalized medicine · 2021Article
- Sickle cell anaemia in vaso-occlusive crisis and acute fatty liver of pregnancy: a case report.Ghana medical journal · 2020Article
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- The Extended Use of Eculizumab in Pregnancy and Complement Activation⁻Associated Diseases Affecting Maternal, Fetal and Neonatal Kidneys-The Future Is Now?Journal of clinical medicine · 2019Review
- Sickle Cell Disease and Pregnancy.Mediterranean journal of hematology and infectious diseases · 2019Review
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Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sickle cell disease is a serious genetic disorder affecting 1/235 births in French Guiana. This study aimed to describe the follow-up of pregnancies among sickle cell disease patients in Cayenne Hospital, in order to highlight the most reported complications. 62 records of pregnancies were analyzed among 44 females with sickle cell disease, between 2007 and 2013. Our results were compared to those of studies conducted in Brazil and Guadeloupe. There were 61 monofetal pregnancies and 2 twin pregnancies, 27 pregnancies among women with SS phenotype, 30 SC pregnancies, and five S-beta pregnancies. The study showed that the follow-up of patients was variable, but no maternal death was found. We also noted that the main maternofetal complications of pregnancies were anemia (36.5%), infection (31.7%), vasoocclusive crisis (20.6%), preeclampsia (17.5%), premature birth (11.1%), intrauterine growth retardation (15.9%), abnormal fetal heart rate (14.3%), and intrauterine fetal death (4.8%). Pregnancies were more at risk among women with SS phenotype. Pregnancy in sickle cell disease patients requires a supported multidisciplinary team including the primary care physician, the obstetrician, and the Integrated Center for Sickle Cell Disease.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.