Evidence map›Paper›PMID 27403155›Full record

ArticleGastroenterology research and practice2016

A Prebiotic Formula Improves the Gastrointestinal Bacterial Flora in Toddlers.

Ya-Ling Chen, Fang-Hsuean Liao, Shyh-Hsiang Lin, Yi-Wen Chien

Abstract read
In one paragraph

Article in Gastroenterology research and practice, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ya-Ling ChenDepartment of Nutrition and Health Sciences, Chang Gung University of Science and Technology, Taoyuan 333, Taiwan.
Fang-Hsuean LiaoSchool of Nutrition and Health Sciences, Taipei Medical University, Taipei 11014, Taiwan.
Shyh-Hsiang LinSchool of Nutrition and Health Sciences, Taipei Medical University, Taipei 11014, Taiwan.ORCID 0000-0002-3723-560X
Yi-Wen ChienSchool of Nutrition and Health Sciences, Taipei Medical University, Taipei 11014, Taiwan.ORCID 0000-0002-7293-5310

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to investigate the effect of enriched 3-prebiotic formula (including inulin, fructooligosaccharides, and galactooligosaccharides) on toddler gut health by measuring fecal microbiota. Our results revealed that the consumption of 3-prebiotic formula three times per day giving total intake of 1.8 g prebiotic ingredients significantly showed the increased number of probiotic Bifidobacterium spp. colonies and the reduced populations of both C. perfringens and total anaerobic bacteria on the fecal bacterial flora in toddlers at 18~36 months. In addition, total organic acids in the fecal samples significantly increased which improves the utilization of bifidus under acidic conditions after consumption of the 3-prebiotic formula. Therefore, using the formula enriched with prebiotic may maintain gut health in toddlers.

Identifiers

PMID27403155
PMCPMC4923535

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.