Evidence map›Paper›PMID 27402955›Full record

ArticleThe Journal of cell biology2016

Spatial resolution of cAMP signaling by soluble adenylyl cyclase.

Giusi Caldieri, Sara Sigismund

Open access · hybridAbstract read
In one paragraph

Article in The Journal of cell biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. GPCR Signaling and Trafficking: The Long and Short of It.Trends in endocrinology and metabolism: TEM · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Giusi CaldieriFondazione Istituto FIRC di Oncologia Molecolare, 20139 Milan, Italy.
Sara SigismundFondazione Istituto FIRC di Oncologia Molecolare, 20139 Milan, Italy sara.sigismund@ifom.eu.
FIRC Institute of Molecular Oncology · IT

Funding

Worldwide Cancer Research 16-1245
6 · The paper itself

Abstract

G protein-coupled receptor signaling starts at the plasma membrane and continues at endosomal stations. In this issue, Inda et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201512075) show that different forms of adenylyl cyclase are activated at the plasma membrane versus endosomes, providing a rationale for the spatial encoding of cAMP signaling.

Indexed as

Signal TransductionAdenylyl CyclasesAnimalsCyclic AMPEndosomesHumansModels, BiologicalReceptors, G-Protein-CoupledSolubilityAdenylyl CyclasesCyclic AMPReceptors, G-Protein-Coupled

Identifiers

PMID27402955
PMCPMC4949454
OpenAlexW2468035098

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.