Evidence map›Paper›PMID 27402907›Full record

ArticleBioinformatics (Oxford, England)2016

BioNetGen 2.2: advances in rule-based modeling.

Leonard A Harris, Justin S Hogg, José-Juan Tapia, John A P Sekar, Sanjana Gupta, Ilya Korsunsky, Arshi Arora, Dipak Barua, Robert P Sheehan, James R Faeder

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 128 papers.

0numbers the graph read from it
0cells of the map it votes in
128citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

128 citing papers in PubMed.

  1. Article
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  12. Spatially structured models of viral dynamics: a scoping review.Microbiology and molecular biology reviews : MMBR · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

68 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Leonard A HarrisDepartment of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Justin S HoggDepartment of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
José-Juan TapiaDepartment of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
John A P SekarDepartment of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Sanjana GuptaDepartment of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Ilya KorsunskyDepartment of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Arshi AroraDepartment of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Dipak BaruaDepartment of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Robert P SheehanDepartment of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
James R FaederDepartment of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

Funding

Regulation of Cardiolin Byosynthesis in Epithelial InjuryP01HL114453 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MALLAMPALLI, RAMA K · 2014 to 2023
$21.3M
TrainingP41GM103712 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FAEDER, JAMES · 2012 to 2021
$16.3M
Autoimmunity and Immunopathology Training ProgramT32AI089443 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SHLOMCHIK, MARK J · 2010 to 2024
$6.6M
Integrated Interdisciplinary, inter-university PhD Program Computational Biology (T32)T32EB009403 · NIBIB · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BAHAR, IVET, BAR-JOSEPH, ZIV · 2009 to 2023
$4.4M
WESTPA: A high-performance framework for simulating at the frontiers of biologyR01GM115805 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LILLIAN T CHONG · 2015 to 2026
$4.0M
Negative Control of IL-17R Signaling: Implications for Fungal ImmunityR01AI107825 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GAFFEN, SARAH L · 2014 to 2018
$1.9M
NHLBI NIH HHS P01 HL114453NIAID NIH HHS R01 AI107825NIBIB NIH HHS T32 EB009403NIGMS NIH HHS P41 GM103712NIGMS NIH HHS R01 GM115805
6 · The paper itself

Abstract

: BioNetGen is an open-source software package for rule-based modeling of complex biochemical systems. Version 2.2 of the software introduces numerous new features for both model specification and simulation. Here, we report on these additions, discussing how they facilitate the construction, simulation and analysis of larger and more complex models than previously possible. AVAILABILITY AND IMPLEMENTATION: Stable BioNetGen releases (Linux, Mac OS/X and Windows), with documentation, are available at http://bionetgen.org Source code is available at http://github.com/RuleWorld/bionetgen CONTACT: bionetgen.help@gmail.comSupplementary information: Supplementary data are available at Bioinformatics online.

Indexed as

BiochemistrySoftwareHumansModels, TheoreticalProgramming Languages

Identifiers

PMID27402907
PMCPMC5079481

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.