ArticleNature communications2016
Highly stable and self-repairing membrane-mimetic 2D nanomaterials assembled from lipid-like peptoids.
Article in Nature communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed.
- Article
- Data-Driven Engineering of Thermostable Collagen-Mimetic Peptoid Triple Helices.Macromolecular rapid communications · 2026Article
- Polymorphism in Self-Assembly of Short Peptoid Sequences.Polymer science & technology (Washington, D.C.) · 2026Article
- Incorporating Gold Nanoparticles with Varying Diameters into Freely Floating Nanosheets via a Biphasic Monolayer Adsorption Assembly Mechanism.Langmuir : the ACS journal of surfaces and colloids · 2025Article
- 2D Assemblies Based on a Tetraphenylethylene D,L-Cyclic Peptide Scaffold.Angewandte Chemie (International ed. in English) · 2025Article
- Assembled peptoid crystalline nanomaterials as carbonic anhydrase mimics for promoted hydration and sequestration of CONature communications · 2025Article
- Cooperative Role of Mixed Solvent in the Evaporation-Induced Self-Assembly of Polypeptoid Nanocrystals.ACS applied nano materials · 2025Article
- Sequence-defined peptoidsChemical science · 2025Article
- 2D Interfacial Crystallization Stabilized by Short-Chain Aliphatic Interfaces.Langmuir : the ACS journal of surfaces and colloids · 2025Article
- A molecular view of peptoid-induced acceleration of calcite growth.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Article
- Assembly of short amphiphilic peptoids into nanohelices with controllable supramolecular chirality.Nature communications · 2024Article
- Article
- Minimal Peptoid Dynamics Inform Self-Assembly Propensity.The journal of physical chemistry. B · 2023Article
- Two-Dimensional Supramolecular Polymerization of DNA Amphiphiles is Driven by Sequence-Dependent DNA-Chromophore Interactions.Angewandte Chemie (International ed. in English) · 2023Article
- Structural Elucidation of a Polypeptoid Chain in a Crystalline Lattice Reveals Key Morphology-Directing Role of the N-Terminus.ACS nano · 2023Article
- Supramolecular systems chemistry through advanced analytical techniques.Analytical and bioanalytical chemistry · 2022Review
- Connexins and Pannexins-Similarities and Differences According to the FOD-M Model.Biomedicines · 2022Article
- Highly stable and tunable peptoid/hemin enzymatic mimetics with natural peroxidase-like activities.Nature communications · 2022Article
- Bottom-up supramolecular assembly in two dimensions.Chemical science · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An ability to develop sequence-defined synthetic polymers that both mimic lipid amphiphilicity for self-assembly of highly stable membrane-mimetic 2D nanomaterials and exhibit protein-like functionality would revolutionize the development of biomimetic membranes. Here we report the assembly of lipid-like peptoids into highly stable, crystalline, free-standing and self-repairing membrane-mimetic 2D nanomaterials through a facile crystallization process. Both experimental and molecular dynamics simulation results show that peptoids assemble into membranes through an anisotropic formation process. We further demonstrated the use of peptoid membranes as a robust platform to incorporate and pattern functional objects through large side-chain diversity and/or co-crystallization approaches. Similar to lipid membranes, peptoid membranes exhibit changes in thickness upon exposure to external stimuli; they can coat surfaces in single layers and self-repair. We anticipate that this new class of membrane-mimetic 2D nanomaterials will provide a robust matrix for development of biomimetic membranes tailored to specific applications.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.