ArticleJournal of diabetes science and technology2017
Changes in HbA1c and Weight Following Transition to Continuous Subcutaneous Insulin Infusion Therapy in Adults With Type 1 Diabetes.
Article in Journal of diabetes science and technology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 25 citations in OpenAlex.
- Prevalence and biopsychosocial factors associated with overweight and obesity in adults with type 1 diabetes.International journal of obesity (2005) · 2026Article
- Transforming diabetes care: The effect of insulin pump technology on quality of life in adults with type 1 diabetes: An interview-based case-control study.Journal of family medicine and primary care · 2025Article
- Insulin Resistance in Type 1 Diabetes: Pathophysiological, Clinical, and Therapeutic Relevance.Endocrine reviews · 2025Review
- Effect of Body Weight on Glycaemic Indices in People with Type 1 Diabetes Using Continuous Glucose Monitoring.Journal of clinical medicine · 2024Article
- An Evaluation of Difficulty in Emotion Regulation, Impulsivity, and Emotional Eating in Children and Adolescents Diagnosed with Type 1 Diabetes Mellitus.Turkish archives of pediatrics · 2024Article
- Article
- Highlighting the Role of Obesity and Insulin Resistance in Type 1 Diabetes and Its Associated Cardiometabolic Complications.Current obesity reports · 2022Review
- Association of Insulin Regimen and Estimated Body Fat Over Time among Youths and Young Adults with Type 1 Diabetes: The SEARCH for Diabetes in Youth Study.Journal of diabetes research · 2022Article
- Marked improvements in glycaemic outcomes following insulin pump therapy initiation in people with type 1 diabetes: a nationwide observational study in Scotland.Diabetologia · 2021Observational
- Canadian Real-World Outcomes of Omnipod Initiation in People with Type 1 Diabetes (COPPER study): Evidence from the LMC Diabetes Registry.Diabetic medicine : a journal of the British Diabetic Association · 2021Observational
- Improved Glycemic Control Following Transition to Tubeless Insulin Pump Therapy in Adults With Type 1 Diabetes.Clinical diabetes : a publication of the American Diabetes Association · 2021Article
- Quality of Life in Children With Diabetes Treated With Insulin Pump Compared With Multiple Daily Injections in Tertiary Care Center.Clinical medicine insights. Endocrinology and diabetes · 2020Article
- Sociodemographic associations of longitudinal adiposity in youth with type 1 diabetes.Pediatric diabetes · 2018Article
- Biopsychosocial Aspects of Weight Management in Type 1 Diabetes: a Review and Next Steps.Current diabetes reports · 2017Review
- Comparison Between Individually and Group-Based Insulin Pump Initiation by Time-Driven Activity-Based Costing.Journal of diabetes science and technology · 2017Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundHistorically, intensive insulin therapy for type 1 diabetes (T1D) has improved glycemic control at the risk of adverse weight gain. The impact of continuous subcutaneous insulin infusion therapy (CSII) on weight in the current era remains unknown. We assessed changes in hemoglobin A1c (HbA1c) and weight in adults with T1D transitioning to CSII at 2 diabetes centers in Denmark and the United States.
methodsPatients with T1D, aged ≥18 years, managed with multiple daily injections (MDI) who transitioned to CSII between 2002 and 2013 were identified using electronic health record data from the Steno Diabetes Center (n = 600) and Joslin Diabetes Center (n = 658). Changes in HbA1c and weight after 1 year was assessed overall and by baseline HbA1c cut points. Multivariate regression assessed correlates of HbA1c reduction.
resultsIn adults with T1D transitioning to CSII, clinically significant HbA1c reductions were found in patients with baseline HbA1c 8.0-8.9% (Steno, -0.7%; Joslin, -0.4%) and baseline HbA1c ≥9.0% (Steno, -1.1%; Joslin, -0.9%) ( P < .005 for all). Overall, there was no significant change in weight after 1 year at either center. Modest (<2%) weight gain was noted in patients with baseline HbA1c ≥9% at Steno (1.1 ± 0.3 kg, P < .0001) and Joslin (1.7 ± 1.1, P < .005). In multivariate models, HbA1c reduction was associated with higher HbA1c, older age, female sex at Steno ( R
conclusionAdults with T1D with suboptimal glycemic control significantly improved HbA1c without a negative impact on weight 1 year after transitioning from MDI to CSII.
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