Evidence map›Paper›PMID 27402168›Full record

ArticleJournal of genetic counseling2017

The Role of Knowledge on Genetic Counseling and Testing in Black Cancer Survivors at Increased Risk of Carrying a BRCA1/2 Mutation.

Alejandra Hurtado-de-Mendoza, Monica C Jackson, Lyndsay Anderson, Vanessa B Sheppard

Open access · bronzeAbstract read
In one paragraph

Article in Journal of genetic counseling, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Trial
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  11. Understanding Medical Mistrust in Black Women at Risk of BRCA 1/2 Mutations.Journal of health disparities research and practice · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Alejandra Hurtado-de-MendozaLombardi Comprehensive Cancer Center, Georgetown University Medical Center, 3300 Whitehaven St. NW, Suite 4100, Washington, DC, 20007, USA. ahd28@georgetown.edu.
Monica C JacksonDepartment of Mathematics and Statistics, American University, Washington, DC, USA.
Lyndsay AndersonCapital Breast Care Center, MedStar Georgetown University Hospital/Lombardi Comprehensive Cancer Center, Washington, DC, USA.
Vanessa B SheppardLombardi Comprehensive Cancer Center, Georgetown University Medical Center, 3300 Whitehaven St. NW, Suite 4100, Washington, DC, 20007, USA.
Georgetown University · USAmerican University · USGeorgetown University Medical Center · US

Funding

Tissue Culture Shared ResourceP30CA051008 · NCI · GEORGETOWN UNIVERSITY · PI Louis M Weiner · 1990 to 2026
$71.5M
PREDICTORS OF ADJUVANT ENDOCRINE THERAPY ADHERENCE IN WOMEN WITH BREAST CANCERR01CA154848 · NCI · GEORGETOWN UNIVERSITY · PI SHEPPARD, VANESSA B · 2011 to 2015
$2.5M
Enhancing at-Risk Latina Women's Use of Genetic Counseling for Hereditary Breast and Ovarian CancerR03CA191543 · NCI · GEORGETOWN UNIVERSITY · PI HURTADO DE MENDOZA CASAUS, ALEJANDRA, SHEPPARD, VANESSA B · 2016 to 2017
$158k
NCI NIH HHS P30 CA051008NCI NIH HHS R01 CA154848NCI NIH HHS R03 CA191543
6 · The paper itself

Abstract

Genetic counseling and testing (GCT) for hereditary breast and ovarian cancers (HBOC) can inform treatment decisions in survivors. Black women at risk of HBOC have lower GCT engagement. There is limited data about Black survivors' experiences. The goals of this study were to: 1) examine the factors associated with HBOC knowledge and 2) assess the impact of knowledge on GCT engagement in a sample of Black survivors at risk of HBOC. Fifty Black at-risk breast/ovarian cancer survivors participated in a telephone-based survey. GCT use was measured across a continuum (awareness, referral, and use). The primary predictor variable was HBOC knowledge. Other clinical, socio-demographic, and psychosocial variables were included. Multiple linear and ordinal regression models (knowledge as the outcome and GCT as the outcome) assessed the predictors of knowledge and GCT engagement. Less than half (48 %) of survivors were referred to or used GCT services. Knowledge was moderate (M = 7.78, SD = 1.61). In the multivariable analysis, lower age (β = -.34, p = .01) and lower stage (β = -.318, p = .017) were associated with higher knowledge. Higher knowledge (β = .567, p = .006) and higher self-efficacy (β = .406, p = .001) were significantly associated with GCT engagement. Future interventions directed at increasing knowledge, self-efficacy, and improving the referral process are warranted.

Indexed as

Genetic CounselingGenetic TestingHealth Knowledge, Attitudes, PracticeAdultBlack or African AmericanFemaleGenes, BRCA1Genes, BRCA2Genetic Predisposition to DiseaseHereditary Breast and Ovarian Cancer SyndromeHumansMiddle AgedMutationSurveys and QuestionnairesSurvivorsUnited StatesBlack womenBRCA1/2 genetic counseling and testingBreast cancerPsychosocial factorsSurvivors

Identifiers

PMID27402168
PMCPMC5233651
OpenAlexW2465193490

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.