Evidence map›Paper›PMID 27402141›Full record

ArticleBMC health services research2016

How hepatitis C patients manage the treatment process of pegylated interferon and ribavirin therapy: a qualitative study.

Shu-Mei Tsai, Jung-Ta Kao, Yun-Fang Tsai

Open access · goldAbstract read
In one paragraph

Article in BMC health services research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Shu-Mei TsaiGraduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, 259, Wen-Hwa 1st Road, Tao-Yuan, 333, Taiwan.
Jung-Ta KaoSchool of Medicine, College of Medicine, China Medical University; Division of Hepato-Gastroenterology, Department of Internal Medicine, China Medical University Hospital, 2, Yuh-Der Road, Taichung, 404, Taiwan.
Yun-Fang TsaiSchool of Nursing, College of Medicine, Chang Gung University; Department of Nursing, Chang Gung University of Science and Technology; Department of Psychiatry, Chang Gung Memorial Hospital at Keelung, 259, Wen-Hwa 1st Road, Tao-Yuan, 333, Taiwan. yftsai@mail.cgu.edu.tw.
Chang Gung University · TWChina Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHepatitis C virus (HCV) infection is a global public health issue. Adequate treatment for hepatitis C patients is important, but anticipated side effects make patients fearful of receiving treatment. Little is known about the experiences of hepatitis C patients who have completed treatment with pegylated interferon and ribavirin. The purpose of this study was to explore the experiences of hepatitis C patients who had undergone therapy with pegylated interferon and ribavirin and gain an understanding of what factors contributed to completion of treatment.

methodThis was a qualitative study with 21 adult hepatitis C patients purposively sampled from outpatient liver clinics of a medical university hospital in Taichung City, Taiwan. Participants had completed 6-12 months of therapy with pegylated interferon and ribavirin. Data were collected through individual, face-to-face, in-depth interviews conducted in the participants' homes from June-October 2013. Data were analysed using conventional content analysis.

resultsData analysis revealed three themes that described the strategies employed to alleviate and ease symptoms and manage the processes involved: restructuring their lifestyle, adopting a positive attitude, and seeking support.

conclusionHepatitis C patients face many challenges during treatment with pegylated interferon and ribavirin. These findings provide knowledge that can be used in designing effective programs to help other Hepatitis C patients manage the side effects of pegylated interferon and ribavirin therapy, complete treatment and improve quality of life.

Indexed as

AdultAgedAged, 80 and overAntiviral AgentsDrug Therapy, CombinationFemaleHepacivirusHepatitis C, ChronicHumansInterferon-alphaMaleMiddle AgedPolyethylene GlycolsPrescription FeesQualitative ResearchQuality of LifeAntiviral AgentsInterferon-alphapeginterferon alfa-2aPolyethylene GlycolsRecombinant ProteinsRibavirinAntiviral treatmentEmploying strategiesHepatitis C experience

Identifiers

PMID27402141
PMCPMC4940691
OpenAlexW2464253639

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.