Evidence map›Paper›PMID 27402108›Full record

ReviewCurrent rheumatology reports2016

Preventive Treatments for Rheumatoid Arthritis: Issues Regarding Patient Preferences.

Axel Finckh, Monica Escher, Matthew H Liang, Nick Bansback

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current rheumatology reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.

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  12. Pre-RA: Can early diagnosis lead to prevention?Best practice & research. Clinical rheumatology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 3 countries.

Axel FinckhDivision of Rheumatology, University Hospitals of Geneva (HUG), 26, Av. Beau-Séjour, CH-1211, Geneva 14, Switzerland. axel.finckh@hcuge.ch.
Monica EscherPain and Palliative Care Consultation, Division of Clinical Pharmacology and Toxicology, University Hospitals of Geneva, Geneva, Switzerland.
Matthew H LiangDivision of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, USA.
Nick BansbackSchool of Population and Public Health, University of British Columbia, Vancouver, Canada.
Brigham and Women's Hospital · USHôpital Beau-Séjour · CHUniversity Hospital of Geneva · CHUniversity of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The detection of biomarkers in the preclinical phase of rheumatoid arthritis (RA) and recent therapeutic advances suggest that it may be possible to identify and treat persons at high risk and to prevent the development of RA. Several trials are ongoing to test the efficacy of a therapeutic intervention in primary prevention. This paper reviews potential populations that might be considered for preventative medication. Further, we review the medications that are being explored to treat individuals considered at high risk of developing RA. Finally, in a group of asymptomatic individuals at high risk of developing RA, we assessed which factors mattered most when considering a preventive therapeutic intervention and what type of preventive treatment would be most acceptable to them. Understanding subjects' perceptions of risks and benefits and willingness to undergo preventive therapy will be important in designing and implementing screening and preventive strategies.

Indexed as

Patient PreferencePrimary PreventionAntirheumatic AgentsArthritis, RheumatoidHumansAntirheumatic AgentsDecision makingPatient preferencesPopulation at riskPreventionPreventive therapyRheumatoid arthritis (RA)

Identifiers

PMID27402108
OpenAlexW2469024649

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.