Association of Autism Spectrum Disorder with Obsessive-Compulsive and Attention-Deficit/Hyperactivity Traits and Response Inhibition in a Community Sample.

Ellen van der Plas, Annie Dupuis, Paul Arnold, Jennifer Crosbie, Russell Schachar

Abstract read

In one paragraph

Article in Journal of autism and developmental disorders, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it

0cells of the map it votes in

11citing papers in PubMed, 1 pooled it

1.0field-weighted citation impact, top 25% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

Zonulin-Dependent Intestinal Permeability in Children Diagnosed with Mental Disorders: A Systematic Review and Meta-Analysis.Nutrients · 2020
Pooled it
Obsessive-Compulsive Traits and Problematic Internet Use Are Increased Among Adults with Autism Spectrum Disorder: Is There a Role of Obsessive Doubts and Communication Impairment?Brain sciences · 2024
Article
Prevalence and Correlates of the Concurrence of Autism Spectrum Disorder and Obsessive Compulsive Disorder in Children and Adolescents: A Systematic Review and Meta-Analysis.Brain sciences · 2024
Review
Identifying Replicable Subgroups in Neurodevelopmental Conditions Using Resting-State Functional Magnetic Resonance Imaging Data.JAMA network open · 2023
Article
The time is ripe for the renaissance of autism treatments: evidence from clinical practitioners.Frontiers in integrative neuroscience · 2023
Article
Paediatrics & child health · 2022
Article
Mental health profiles of autistic children and youth during the COVID-19 pandemic.Paediatrics & child health · 2022
Article
Clinical validation of the parent-report Toronto Obsessive-Compulsive Scale (TOCS): A pediatric open-source rating scale.JCPP advances · 2021
Article
The Monash Autism-ADHD genetics and neurodevelopment (MAGNET) project design and methodologies: a dimensional approach to understanding neurobiological and genetic aetiology.Molecular autism · 2021
Article
Examining overlap and homogeneity in ASD, ADHD, and OCD: a data-driven, diagnosis-agnostic approach.Translational psychiatry · 2019
Article
Structural neuroimaging correlates of social deficits are similar in autism spectrum disorder and attention-deficit/hyperactivity disorder: analysis from the POND Network.Translational psychiatry · 2019
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Ellen van der PlasDepartment of Psychiatry, The Hospital for Sick Children, 555 University Avenue, Toronto, ON, M5G 1X8, Canada.

Annie DupuisDepartment of Psychiatry, The Hospital for Sick Children, 555 University Avenue, Toronto, ON, M5G 1X8, Canada.

Paul ArnoldDepartment of Psychiatry, The University of Toronto, 250 College Street, Toronto, ON, M5T 1R8, Canada.

Jennifer CrosbieDepartment of Psychiatry, The Hospital for Sick Children, 555 University Avenue, Toronto, ON, M5G 1X8, Canada.

Russell SchacharDepartment of Psychiatry, The Hospital for Sick Children, 555 University Avenue, Toronto, ON, M5G 1X8, Canada. russell.schachar@sickkids.ca.

Hospital for Sick Children · CAGenome Canada · CAUniversity of Toronto · CA

Funding

CIHR 44070CIHR 74699CIHR MOP 64277

6 · The paper itself

Abstract

We examined co-occurrence of autism spectrum disorder (ASD) with (traits of) attention-deficit/hyperactivity (ADHD), obsessive-compulsive (OCD) and inhibition deficits in a community sample (n = 16,676) and tested whether having a sibling with ASD manifested in increased features of ADHD, OCD or inhibition deficits. Individuals with ASD had increased ADHD and OCD traits compared with individuals without ASD. Individuals with a sibling with ASD exhibited more ADHD traits than did individuals whose sibling did not have ASD. The "sibling effect" on manifestation of ADHD traits was observed in individuals with and without ASD. Having a sibling with ASD did not affect OCD traits. Inhibition was impaired in individuals with ASD who had a sibling with ASD only.

Indexed as

Inhibition, PsychologicalPsychomotor PerformanceAdolescentAttention Deficit Disorder with HyperactivityAutism Spectrum DisorderChildFemaleHumansMaleObsessive-Compulsive DisorderPhenotypeReaction TimeSiblingsAttention/deficits hyperactivity disorderAutismCommunity sampleFamilialObsessive compulsive disorderTraits

Identifiers

PMID27401994

DOI10.1007/s10803-016-2853-y

OpenAlexW2460742235

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.