Evidence map›Paper›PMID 27401949›Full record

ArticleThe American journal of medicine2016

Association of 30-Day All-Cause Readmission with Long-Term Outcomes in Hospitalized Older Medicare Beneficiaries with Heart Failure.

Cherinne Arundel, Phillip H Lam, Rahul Khosla, Marc R Blackman, Gregg C Fonarow, Charity Morgan, Qing Zeng, Ross D Fletcher, Javed Butler, Wen-Chih Wu and 7 more

Abstract read
In one paragraph

Article in The American journal of medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Cherinne Arundel *Veterans Affairs Medical Center, Washington, DC.
Phillip H Lam *Georgetown University Hospital/Washington Hospital Center, Washington, DC.
Rahul KhoslaVeterans Affairs Medical Center, Washington, DC.
Marc R BlackmanVeterans Affairs Medical Center, Washington, DC.
Gregg C FonarowUniversity of California, Los Angeles, CA.
Charity MorganUniversity of Alabama at Birmingham, Birmingham, AL.
Qing ZengGeorge Washington University, Washington, DC.
Ross D FletcherVeterans Affairs Medical Center, Washington, DC.
Javed ButlerState University of New York, Stony Brook, NY.
Wen-Chih WuVeterans Affairs Medical Center, Providence, RI.
Prakash DeedwaniaUniversity of California San Francisco, CA.
Thomas E LoveCase Western Reserve University, Cleveland, OH.
Michel WhiteMontreal Heart Institute, Montreal, Canada.
Wilbert S AronowNew York Medical College, Valhalla, NY.
Stefan D AnkerUniversity of Göttingen, Göttingen, Germany.
Richard M AllmanDepartment of Veterans Affairs, Geriatrics and Extended Care Services, Washington, DC.
Ali AhmedVeterans Affairs Medical Center, Washington, DC.

Funding

Maternal Morbidity and Mortality: Risk Factors, Early Detection and Personalized InterventionUL1TR001409 · NCATS · GEORGETOWN UNIVERSITY · PI GONDRE-LEWIS, MARJORIE C, MELLMAN, THOMAS A · 2015 to 2024
$37.8M
Heart failure, chronic kidney disease, and renin-angiotensin system inhibitionR01HL085561 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI AHMED, ALI · 2006 to 2009
$1.5M
Neurohormonal Blockade and Outcomes in Diastolic Heart FailureR01HL097047 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI AHMED, ALI · 2009 to 2010
$915k
NCATS NIH HHS UL1 TR001409NHLBI NIH HHS R01 HL085561NHLBI NIH HHS R01 HL097047
6 · The paper itself

Abstract

backgroundHeart failure is the leading cause for 30-day all-cause readmission. We examined the impact of 30-day all-cause readmission on long-term outcomes and cost in a propensity score-matched study of hospitalized patients with heart failure.

methodsOf the 7578 Medicare beneficiaries discharged with a primary diagnosis of heart failure from 106 Alabama hospitals (1998-2001) and alive at 30 days after discharge, 1519 had a 30-day all-cause readmission. Using propensity scores for 30-day all-cause readmission, we assembled a matched cohort of 1516 pairs of patients with and without a 30-day all-cause readmission, balanced on 34 baseline characteristics (mean age 75 years, 56% women, 24% African American).

resultsDuring 2-12 months of follow-up after discharge from index hospitalization, all-cause mortality occurred in 41% and 27% of matched patients with and without a 30-day all-cause readmission, respectively (hazard ratio 1.68; 95% confidence interval 1.48-1.90; P <.001). This harmful association of 30-day all-cause readmission with mortality persisted during an average follow-up of 3.1 (maximum, 8.7) years (hazard ratio 1.33; 95% confidence interval 1.22-1.45; P <.001). Patients with a 30-day all-cause readmission had higher cumulative all-cause readmission (mean, 6.9 vs 5.1; P <.001), a longer cumulative length of stay (mean, 51 vs 43 days; P <.001), and a higher cumulative cost (mean, $38,972 vs $34,025; P = .001) during 8.7 years of follow-up.

conclusionsAmong Medicare beneficiaries hospitalized for heart failure, 30-day all-cause readmission was associated with a higher risk of subsequent all-cause mortality, higher number of cumulative all-cause readmission, longer cumulative length of stay, and higher cumulative cost.

Indexed as

MortalityAgedAged, 80 and overAlabamaCase-Control StudiesCohort StudiesComorbidityCoronary Artery DiseaseDiabetes MellitusFemaleFollow-Up StudiesHeart FailureHospitalizationHumansMaleMedicare30-Day all-cause readmissionAll-cause mortalityCostHeart failureMedicare beneficiaries

Identifiers

PMID27401949
PMCPMC5075494

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.