Evidence map›Paper›PMID 27401847›Full record

ArticleJournal of the American Geriatrics Society2016

Predicting 2-Year Risk of Developing Pneumonia in Older Adults without Dementia.

Michael L Jackson, Rod Walker, Sei Lee, Eric Larson, Sascha Dublin

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Michael L JacksonGroup Health Research Institute, Seattle, Washington.
Rod WalkerGroup Health Research Institute, Seattle, Washington.
Sei LeeDivision of Geriatrics, University of California at San Francisco, San Francisco, California.
Eric LarsonGroup Health Research Institute, Seattle, Washington.
Sascha DublinGroup Health Research Institute, Seattle, Washington.
Kaiser Permanente Washington Health Research Institute · USUniversity of California, San Francisco · US

Funding

Furthering scientific understanding of mechanisms underlying resilience to the effects of AD pathology by incorporating state of the art quantification of gliosis, inflammation, & synaptic toxicityU01AG006781 · NIA · UNIVERSITY OF WASHINGTON · PI CRANE, PAUL K, LARSON, ERIC B · 1986 to 2020
$39.3M
VARC CoreP30AG044281 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Alexander Keliimoeanu Smith · 2013 to 2026
$19.9M
Pharmacepidemiology in the elderly: medications pneumonia risk and confoundingK23AG028954 · NIA · KAISER FOUNDATION HEALTH PLAN OF WASHINGTON · PI DUBLIN, SASCHA · 2007 to 2011
$864k
NIA NIH HHS K23 AG028954NIA NIH HHS P30 AG044281NIA NIH HHS U01 AG006781
6 · The paper itself

Abstract

objectivesTo develop three prognostic indices of varying degree of required detail for 2-year pneumonia risk in older adults.

designRetrospective cohort study.

settingGroup Health (GH), an integrated healthcare delivery system.

participantsCommunity-dwelling dementia-free individuals aged 65 and older who had been GH members for at least 2 years before start of follow-up and were enrolled in the Adult Changes in Thought study (N = 3,375; development cohort, n = 2,250; validation cohort, n = 1,125. MEASUREMENTS: Potential pneumonia risk factors were identified from questionnaire data and interviewer assessments of functional status, medical history, smoking and alcohol use, cognitive function, personal care, and problem solving. Risk factors were also identified based on physical measures such as grip strength and gait speed and administrative database information on comorbid illnesses, laboratory tests, and prescriptions dispensed. Incident community-acquired pneumonia was defined presumptively from administrative data and validated using medical record review.

resultsParticipants (59% female) contributed 12,998 visits at which risk factors were assessed; 642 pneumonia events were observed during follow-up. Age, sex, chronic obstructive pulmonary disease, congestive heart failure, body mass index, and use of inhaled or oral corticosteroids were critical predictors in all prognostic indices. A risk score based on these seven variables, information on which is commonly available in electronic medical records (EMRs), had equal or better performance (c-index = 0.69 in the validation cohort) than scores including more-detailed data such as functional status.

conclusionData commonly available in EMRs can stratify older adults into groups with varying subsequent 2-year pneumonia risk.

Indexed as

AgedAged, 80 and overCommunity-Acquired InfectionsFemaleGeriatric AssessmentHumansMalePneumoniaPrognosisRetrospective StudiesRisk FactorsSurveys and QuestionnairesWashingtonaged 80 and olderpneumoniapredictive value of tests

Identifiers

PMID27401847
PMCPMC4943660
OpenAlexW2467588870

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.