Evidence map›Paper›PMID 27401741›Full record

Observational studyHeart and vessels2017

Estimated glucose disposal rate and long-term survival in type 2 diabetes after coronary artery bypass grafting.

Thomas Nyström, Martin J Holzmann, Björn Eliasson, Ann-Marie Svensson, Jeanette Kuhl, Ulrik Sartipy

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Heart and vessels, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

  1. Pooled it
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  11. Glycated Haemoglobin (HbAJournal of clinical medicine · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Thomas NyströmDepartment of Clinical Science and Research, Karolinska Institutet, Stockholm, Sweden.
Martin J HolzmannDepartment of Emergency Medicine, Karolinska University Hospital, Stockholm, Sweden.
Björn EliassonInstitute of Medicine, University of Gothenburg, Sahlgrenska University Hospital, Göteborg, Sweden.
Ann-Marie SvenssonCentre of Registers in Region Västra Götaland, Göteborg, Sweden.
Jeanette KuhlDepartment of Cardiovascular Medicine, Danderyds Hospital, Stockholm, Sweden.
Ulrik SartipyDepartment of Cardiothoracic Surgery and Anesthesiology, Karolinska University Hospital, 171 76, Stockholm, Sweden. Ulrik.Sartipy@karolinska.se.ORCID http://orcid.org/0000-0003-2707-0263
Karolinska University Hospital · SEDanderyds sjukhus · SEKarolinska Institutet · SERegion Västra Götaland · SESahlgrenska University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We performed a nationwide population-based cohort study to investigate the association between estimated glucose disposal rate (eGDR) and long-term survival after coronary artery bypass grafting (CABG) in patients with type 2 diabetes. All patients who underwent primary CABG in Sweden from 2006 to 2013 were identified from the SWEDEHEART register and by record linkage to the National Diabetes Register; all patients with type 2 diabetes were included and formed the study population. Patients were followed until 2013 through national registers for major adverse cardiovascular events and death from any cause. eGDR was calculated using waist circumference, hemoglobin A1c, and presence or the absence of hypertension. The association between eGDR and death was estimated using multivariable Cox regression. A total of 3256 patients were included. During a mean follow-up of 3.1 years (10,227 person-years), in total, 14 % patients died: 17 % (n = 186) in the 1st tertile (lowest eGDR), 14 % (n = 145) in the 2nd tertile, and 13 % (n = 133) in the 3rd tertile (highest eGDR). There was a significant association between eGDR and increased risk of death: adjusted hazard ratio (95 % confidence interval): 1.46 (1.12-1.90) for the 1st eGDR tertile compared to the 3rd and highest eGDR tertile. In conclusion, patients with type 2 diabetes who underwent CABG, a low eGDR, were associated with an increased risk of long-term all-cause mortality that was independent of other cardiovascular and metabolic risk factors. Insulin resistance measured by eGDR could be a useful risk marker in patients with type 2 diabetes and ischemic heart disease.

Indexed as

Coronary Artery BypassAgedBlood GlucoseCohort StudiesCoronary Artery DiseaseDiabetes Mellitus, Type 2FemaleGlycated HemoglobinHumansInsulin ResistanceMaleMiddle AgedMultivariate AnalysisRegistriesRisk FactorsSurvival AnalysisBlood GlucoseGlycated HemoglobinCoronary artery diseaseDiabetes mellitusInsulin resistance: coronary artery bypass graft surgery

Identifiers

PMID27401741
OpenAlexW2474363442

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.