ArticleYonsei medical journal2016
Risk Factors for the Rupture of Bifurcation Intracranial Aneurysms Using CT Angiography.
Article in Yonsei medical journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed.
- Comparison of Woven EndoBridge and stent-assisted coiling for treatment of acutely ruptured wide-neck bifurcation aneurysms: Single-center experience.Journal of cerebrovascular and endovascular neurosurgery · 2025Article
- Fluid structure Interaction analysis for rupture risk assessment in patients with middle cerebral artery aneurysms.Scientific reports · 2025Article
- The relationship between symptomatic status and aneurysm wall enhancement characteristics of single unruptured intracranial aneurysm.Radiologie (Heidelberg, Germany) · 2024Article
- Dynamic evaluation of unruptured intracranial aneurysms by 4D-CT angiography: comparison with digital subtraction angiography (DSA) and surgical findings.BMC medical imaging · 2023Article
- Morphological Characteristics of Ruptured Brain Aneurysms: A Systematic Literature Review and Meta-Analysis.Stroke (Hoboken, N.J.) · 2023Article
- Different Hemodynamic Characteristics and Resulting in Different Risks of Rupture Between Wide-Neck and Narrow-Neck Aneurysms.Frontiers in neurology · 2022Article
- Quantitative analysis of flow vortices: differentiation of unruptured and ruptured medium-sized middle cerebral artery aneurysms.Acta neurochirurgica · 2021Article
- Intracranial aneurysm management in patients with late-onset Pompe disease (LOPD).Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021Article
- U-Shaped Association of Aspect Ratio and Single Intracranial Aneurysm Rupture in Chinese Patients: A Cross-Sectional Study.Frontiers in neurology · 2021Article
- Current Treatment of Anterior Communicating Artery Aneurysms: Single Center Study.Brain sciences · 2020Article
- A Simple Scoring Model for Prediction of Rupture Risk of Anterior Communicating Artery Aneurysms.Frontiers in neurology · 2019Article
- Therapeutic evaluation of a patient with ruptured intracranial aneurysm without subarachnoid hemorrhage by CT imaging: a case report.BMC neurology · 2018Article
- Wall enhancement ratio and partial wall enhancement on MRI associated with the rupture of intracranial aneurysms.Journal of neurointerventional surgery · 2018Article
- Risk factors for ruptured intracranial aneurysms.The Indian journal of medical research · 2018Article
- Difference in aneurysm characteristics between ruptured and unruptured aneurysms in patients with multiple intracranial aneurysms.Surgical neurology international · 2018Article
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6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo investigate the clinical and morphological characteristics in relation to risk of bifurcation intracranial aneurysm rupture. MATERIALS AND
methodsData from 202 consecutive patients with 219 bifurcation aneurysms (129 ruptured and 90 unruptured) managed at the authors' facility between August 2011 and July 2014 were retrospectively reviewed. Based on their clinical records and CT angiographic findings, the ability of risk factors to predict aneurysm rupture was assessed using statistical methods.
resultsAge, hypertension, diabetes mellitus, and cerebral atherosclerosis were negatively correlated with aneurysm rupture. Aneurysms located in the middle cerebral artery, daughter artery ratio, lateral angle ratio (LA ratio), and neck width were negatively correlated with rupture. Aneurysms located in the anterior communicating artery, irregularity, with daughter sac, depth, width, maximum size, aspect ratio (AR), depth-to-width ratio, and bottleneck factor were significantly and positively correlated with rupture. Binary logistic regression model revealed that irregular shape [odds ratio (OR) 6.598] and AR (OR 3.507) strongly increased the risk of bifurcation aneurysm rupture, while age (OR 0.434), cerebral atherosclerosis (OR 0.125), neck width (OR 0.771), and LA ratio (OR 0.267) were negatively correlated with rupture (p<0.05). Receiver operating characteristic analysis revealed the threshold values of AR and LA ratio to be 1.18 and 1.50, respectively.
conclusionAge (≥60 yr), cerebral atherosclerosis, and aneurysms with a larger neck width and larger LA ratio are protective factors against bifurcation aneurysm rupture. An aneurysm with an irregular shape and an increased AR reflect the greater likelihood of a rupture.
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