ArticleYonsei medical journal2016
Association between Vitamin D Deficiency and Anemia in Patients with End-Stage Renal Disease: A Cross-Sectional Study.
Article in Yonsei medical journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 19 citations in OpenAlex.
- Association of Serum 1,25-Dihydroxyvitamin D Levels with Erythropoietin Resistance Index-Based Relative Erythropoiesis-Stimulating Agent Hyporesponsiveness in Pre-Dialysis Chronic Kidney Disease.International journal of molecular sciences · 2026Article
- Impact of Side Effects on Anemia Therapy Compliance.Nutrients · 2025Observational
- Association between anemia and vitamin D deficiency in German seniors : A retrospective data analysis.Zeitschrift fur Gerontologie und Geriatrie · 2024Article
- Risk factors and current state of therapy for anemia after kidney transplantation.Frontiers in medicine · 2023Review
- Relationship between serum vitamin D3 concentration and anaemia in patients with chronic kidney disease in China.The Journal of international medical research · 2021Article
- Vitamin D and hematinic deficiencies in patients with recurrent aphthous stomatitis.Clinical oral investigations · 2020Article
- Association Between Dyslipidemia and Serum Level of 25-Hydroxyvitamin-D in Early Chronic Kidney Disease, Not on Dialysis: An Observational Cross-Sectional Study from the Himalayan Country.International journal of nephrology and renovascular disease · 2020Article
- Multiple micronutrient status and predictors of anemia in young children aged 12-23 months living in New Delhi, India.PloS one · 2019Article
- Association of Vitamin D and secondary hyperparathyroidism with anemia in diabetic kidney disease.Journal of family medicine and primary careArticle
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeDespite new treatment strategies, anemia remains the most prevalent complication in patients with end-stage renal disease (ESRD). We investigated whether 25-hydroxyvitamin D [25(OH)D3] deficiency was associated with anemia in ESRD patients. MATERIALS AND
methodsWe reviewed the medical records of 410 ESRD patients who had undergone renal transplantation (RTx) at Yonsei University Health System and who had 25(OH)D3 levels measured at the time of RTx. Patients were divided into two groups based on baseline 25(OH)D3 concentrations: group 1, 25(OH)D3 levels <10 ng/mL; and group 2, 25(OH)D3 levels ≥10 ng/mL.
resultsUsing multivariate regression models, 25(OH)D3, age, and erythrocyte-stimulating agent (ESA) dose were found to be significantly associated with hemoglobin (Hb) levels [25(OH)D3: β=0.263, p<0.001; age: β=0.122, p=0.010; ESA dose: β=-0.069, p=0.005]. In addition, logistic regression analysis revealed that patients in group 1 had a significantly higher risk for developing anemia (Hb level <10 g/dL) compared to group 2 patients, even after adjusting for potential risk factors for anemia (odds ratio=3.857; confidence interval=1.091-13.632; p=0.036).
conclusion25(OH)D3 deficiency was significantly associated with anemia in patients with ESRD. Randomized controlled trials are needed to determine whether vitamin D supplementation can improve anemia in these patients.
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