ArticleNetherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation2016
Psychological distress and personality factors in takotsubo cardiomyopathy.
Article in Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Prodromal Symptoms of Acute Myocardial Infarction in Women: A Systematic Review of Current Evidence.Nursing open · 2025Pooled it
- Heart rate variability alterations in takotsubo syndrome and related association with psychological factors: a systematic review and meta-analysis.Scientific reports · 2023Pooled it
- Translation, validation, predictive analysis of the Italian version of the McSweeney Acute and Prodromal Myocardial Infarction Symptom Survey and symptom cluster characterization in women.International journal of nursing studies advances · 2026Article
- Biological stress, self-rated stress, anxiety and depression in women with takotsubo syndrome.BMC cardiovascular disorders · 2026Article
- Meaning of life and stress-coping strategies for broken heart syndrome patients.Scientific reports · 2025Article
- Emotional Dysregulation and Autonomic Dysfunction in Takotsubo Cardiomyopathy Patients.Cureus · 2025Article
- Psychosocial and clinical characteristics in Takotsubo syndrome.Biology of sex differences · 2025Article
- Deciphering the Psychological Characteristics of Takotsubo Cardiomyopathy and Acute Myocardial Infarction.Journal of personalized medicine · 2024Article
- Psychosocial and clinical characteristics of a patient with Takotsubo syndrome and her healthy monozygotic twin: a case report.European heart journal. Case reports · 2022Article
- Psychological Characteristics of Patients with Takotsubo Syndrome and Patients with Acute Coronary Syndrome: An Explorative Study toward a Better Personalized Care.Journal of personalized medicine · 2022Article
- Smidt Heart Institute Takotsubo Registry - Study design and baseline characteristics.American heart journal plus : cardiology research and practice · 2022Article
- Prevalence Estimates, Severity, and Risk Factors of Depressive Symptoms among Coronary Artery Disease Patients after Ten Days of Percutaneous Coronary Intervention.Clinical practice and epidemiology in mental health : CP & EMH · 2021Article
- Traumatic Events, Personality and Psychopathology in Takotsubo Syndrome: A Systematic Review.Frontiers in psychology · 2019Review
- Takotsubo Cardiomyopathy-Acute Cardiac Dysfunction Associated With Neurological and Psychiatric Disorders.Frontiers in neurology · 2019Review
- Association of prolonged QTc interval with Takotsubo cardiomyopathy: A neurocardiac syndrome inside the mystery of the insula of Reil.Clinical cardiology · 2018Review
- Cardiac disease and depression; a direct association?Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2016Article
- Takotsubo cardiomyopathy - stunning views on the broken heart.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2016Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTakotsubo cardiomyopathy (TCC) is a transient condition characterised by severe left ventricular dysfunction combined with symptoms and signs mimicking myocardial infarction. Emotional triggers are common, but little is known about the psychological background characteristics of TCC. This study examined whether patients with TTC have higher levels of psychological distress (depressive symptoms, perceived stress, general anxiety), illness-related anxiety and distinct personality factors compared with healthy controls and patients with heart failure. METHODS AND
resultsPatients with TCC (N = 18; mean age 68.3 ± 11.7 years, 77.8 % women) and two comparison groups (healthy controls: N = 19, age 60.0 ± 7.6, 68.4 % women and patients with chronic heart failure: N = 19, age 68.8 ± 10.1, 68.4 % women) completed standardised questionnaires to measure depression (PHQ‑9), perceived stress (PSS-10), general anxiety (GAD-7), illness-related anxiety (WI-7) and personality factors (NEO-FFI and DS-14). Psychological measures were obtained at 23 ± 18 months following the acute TTC event. Results showed that patients with TCC had higher levels of depressive symptoms (5.2 ± 5.2 vs. 2.5 ± 2.4, p = 0.039) and illness-related anxiety (2.1 ± 1.7 vs. 0.7 ± 1.3, p = 0.005) compared with healthy controls. Patients with TCC did not display significantly elevated perceived stress (p = 0.072) or general anxiety (p = 0.170). Regarding personality factors, levels of openness were lower in TCC compared with healthy controls (34.2 ± 4.3 vs. 38.2 ± 5.6, p = 0.021). No differences between TCC and heart failure patients were found regarding the psychological measures.
conclusionsTCC is associated with higher levels of depressive symptoms, more illness-related anxiety and less openness compared with healthy controls. These data suggest that TCC is associated with adverse psychological factors that may persist well after the acute episode.
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