Evidence map›Paper›PMID 27401514›Full record

Trial reportJournal of pain and symptom management2016

Randomized Pilot Trial of a Telephone Symptom Management Intervention for Symptomatic Lung Cancer Patients and Their Family Caregivers.

Catherine E Mosher, Joseph G Winger, Nasser Hanna, Shadia I Jalal, Lawrence H Einhorn, Thomas J Birdas, DuyKhanh P Ceppa, Kenneth A Kesler, Jordan Schmitt, Deborah A Kashy and 1 more

Open access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of pain and symptom management, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 12 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 12 syntheses or guidelines pooled it, 92 citations in OpenAlex.

  1. Effectiveness of interventions targeting social constraints among adults with cancer and their caregivers: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  5. Nurse-led telehealth interventions for symptom management in patients with cancer receiving systemic or radiation therapy: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Pooled it
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  7. Telephone interventions for symptom management in adults with cancer.The Cochrane database of systematic reviews · 2020
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  10. Association between dyadic interventions and outcomes in cancer patients: a meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019
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  13. Randomized Controlled Trial of Acceptance and Commitment Therapy for Fatigue Interference With Functioning in Metastatic Breast Cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2025
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  20. Acceptance and commitment therapy for symptom interference in metastatic breast cancer patients: a pilot randomized trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Catherine E MosherDepartment of Psychology, Indiana University-Purdue University Indianapolis, Indianapolis, Indiana, USA. Electronic address: cemosher@iupui.edu.
Joseph G WingerDepartment of Psychology, Indiana University-Purdue University Indianapolis, Indianapolis, Indiana, USA.
Nasser HannaDepartment of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Shadia I JalalDepartment of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA; Richard L. Roudebush Veterans Affairs Medical Center, Indianapolis, Indiana, USA.
Lawrence H EinhornDepartment of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Thomas J BirdasDepartment of Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.
DuyKhanh P CeppaDepartment of Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Kenneth A KeslerDepartment of Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Jordan SchmittDepartment of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA; Richard L. Roudebush Veterans Affairs Medical Center, Indianapolis, Indiana, USA.
Deborah A KashyDepartment of Psychology, Michigan State University, East Lansing, Michigan, USA.
Victoria L ChampionIndiana University School of Nursing, Indianapolis, Indiana, USA.
Indiana University School of MedicineIndiana University – Purdue University Indianapolis · USRichard L. Roudebush VA Medical Center · USUniversity of Indianapolis · USMichigan State University · US

Funding

Telephone Symptom Management for Advanced Lung Cancer Patients and CaregiversK07CA168883 · NCI · INDIANA UNIVERSITY INDIANAPOLIS · PI MOSHER, CATHERINE E · 2013 to 2017
$682k
Research and Training for Behavioral Oncology InterventionsK05CA175048 · NCI · INDIANA UNIVERSITY INDIANAPOLIS · PI CHAMPION, VICTORIA LEE · 2014 to 2018
$484k
NCI NIH HHS K05 CA175048NCI NIH HHS K07 CA168883
6 · The paper itself

Abstract

contextLung cancer is one of the most common cancers affecting both men and women and is associated with high symptom burden and psychological distress. Lung cancer patients' family caregivers also show high rates of distress. However, few interventions have been tested to alleviate significant problems of this population.

objectivesThis study examined the preliminary efficacy of telephone-based symptom management (TSM) for symptomatic lung cancer patients and their family caregivers.

methodsSymptomatic lung cancer patients and caregivers (n = 106 dyads) were randomly assigned to four sessions of TSM consisting of cognitive-behavioral and emotion-focused therapy or an education/support condition. Patients completed measures of physical and psychological symptoms, self-efficacy for managing symptoms, and perceived social constraints from the caregiver; caregivers completed measures of psychological symptoms, self-efficacy for helping the patient manage symptoms and managing their own emotions, perceived social constraints from the patient, and caregiving burden.

resultsNo significant group differences were found for all patient outcomes and caregiver self-efficacy for helping the patient manage symptoms and caregiving burden at two- and six-weeks post-intervention. Small effects in favor of TSM were found regarding caregiver self-efficacy for managing their own emotions and perceived social constraints from the patient. Study outcomes did not significantly change over time in either group.

conclusionFindings suggest that our brief telephone-based psychosocial intervention is not efficacious for symptomatic lung cancer patients and their family caregivers. Next steps include examining specific intervention components in relation to study outcomes, mechanisms of change, and differing intervention doses and modalities.

Indexed as

CaregiversCognitive Behavioral TherapyPatient Education as TopicTelemedicineAdultAgedAged, 80 and overDisease ManagementFemaleHumansLung NeoplasmsMaleMiddle AgedPilot ProjectsSelf EfficacySelf Reportcognitive-behavioraldistressfamily caregiversLung cancerpsychosocial interventionssymptom management

Identifiers

PMID27401514
PMCPMC5075493
OpenAlexW2473088790

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.