Evidence map›Paper›PMID 27401417›Full record

ArticleAnnals of family medicine2016

Prevalence of Prediabetes and Abdominal Obesity Among Healthy-Weight Adults: 18-Year Trend.

Arch G Mainous, Rebecca J Tanner, Ara Jo, Stephen D Anton

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Annals of family medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05413486 (Circadian Disturbances in People With Mental Disease), which is not on this map. Cited by 34 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 2 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05413486 unknown statusnot on this mapstarted 2022, after this paper: background citation

Circadian Disturbances in People With Mental Disease

TypeobservationalSponsorEsbjerg Hospital - University Hospital of Southern DenmarkRan2022 to 2024Enrolled86ConditionsBipolar Disorder, Schizophrenia, Obesity, Circadian Rhythm DisordersArmsObservational
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Arch G MainousDepartment of Health Services Research, Management, and Policy, University of Florida, Gainesville, Florida Department of Community Health and Family Medicine, University of Florida, Gainesville, Florida arch.mainous@ufl.edu.
Rebecca J TannerDepartment of Health Services Research, Management, and Policy, University of Florida, Gainesville, Florida.
Ara JoDepartment of Health Services Research, Management, and Policy, University of Florida, Gainesville, Florida.
Stephen D AntonDepartment of Aging and Geriatric Research, University of Florida, Gainesville, Florida.
University of Florida · USUniversity of Florida Health · US

Funding

University of Florida Older Americans Independence Center (OAIC)P30AG028740 · NIA · UNIVERSITY OF FLORIDA · PI CHRISTIAAN LEEUWENBURGH · 2007 to 2026
$22.8M
NIA NIH HHS P30 AG028740
6 · The paper itself

Abstract

purposeTrends in sedentary lifestyle may have influenced adult body composition and metabolic health among individuals at presumably healthy weights. This study examines the nationally representative prevalence of prediabetes and abdominal obesity among healthy-weight adults in 1988 through 2012.

methodsWe analyzed the National Health and Nutrition Examination Survey (NHANES) III (1988-1994) and NHANES for the years 1999 to 2012, focusing on adults aged 20 years and older who have a body mass index (BMI) of 18.5 to 24.99 and do not have diabetes, either diagnosed or undiagnosed. We defined prediabetes using glycated hemoglobin (HbA1c) level ranges from 5.7% to 6.4%, as specified by the American Diabetes Association. Abdominal obesity was measured by waist circumference and waist-to-height ratio.

resultsThe prevalence of prediabetes among healthy-weight adults, aged 20 years and older and without diagnosed or undiagnosed diabetes, increased from 10.2% in 1988-1994 to 18.5% in 2012. Among individuals aged 45 years and older, the prevalence of prediabetes increased from 22.0% to 33.1%. The percentage of adults aged 20 years and older with an unhealthy waist circumference increased from 5.6% in 1988-1994 to 7.6% in 2012. The percentage of individuals with an unhealthy waist-to-height ratio increased from 27.2% in 1988-1994 to 33.7% in 2012. Adjusted models found that measures of abdominal obesity were not independent predictors of prediabetes among adults with a healthy BMI.

conclusionsAmong individuals within a healthy BMI range, the prevalence of prediabetes and abdominal obesity has substantially increased. Abdominal obesity does not appear to be the primary cause of the increase.

Indexed as

Body WeightAdultAgedBody CompositionBody Mass IndexDiabetes MellitusFemaleGlycated HemoglobinHumansLogistic ModelsMaleMiddle AgedNutrition SurveysObesity, AbdominalPrediabetic StatePrevalenceGlycated Hemoglobindiabetes type IIhyperglycemiaprediabetesprediabetic stateprevalenceprevention

Identifiers

PMID27401417
PMCPMC4940459
OpenAlexW2485872072

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.