Evidence map›Paper›PMID 27401353›Full record

SynthesisBMJ open2016

Is coffee consumption associated with a lower risk of hyperuricaemia or gout? A systematic review and meta-analysis.

Yi Zhang, Tuo Yang, Chao Zeng, Jie Wei, Hui Li, Yi-Lin Xiong, Ye Yang, Xiang Ding, Guanghua Lei

Erratum issuedAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMJ open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  14. Impact of Coffee/Green Tea/Soft Drink Consumption on the Risk of Hyperuricemia: A Cross-Sectional Study.International journal of environmental research and public health · 2021
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Yi ZhangDepartment of Orthopaedics, Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Tuo YangDepartment of Orthopaedics, Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Chao ZengDepartment of Orthopaedics, Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Jie WeiDepartment of Epidemiology and Health Statistics, School of Public Health, Central South University, Changsha, Hunan Province, China.
Hui LiDepartment of Orthopaedics, Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Yi-Lin XiongDepartment of Orthopaedics, Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Ye YangDepartment of Orthopaedics, Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Xiang DingDepartment of Orthopaedics, Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Guanghua LeiDepartment of Orthopaedics, Xiangya Hospital, Central South University, Changsha, Hunan Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo examine the associations of coffee consumption with the serum uric acid (SUA) level, hyperuricaemia (HU) and gout.

designSystematic review and meta-analysis. DATA SOURCES AND STUDY ELIGIBILITY CRITERIA: A comprehensive literature search up to April 2015, using PubMed and EMBASE databases, was conducted to identify the observational researches that examined the associations of coffee consumption with the SUA level, HU and gout. The standard mean difference (SMD), OR, relative risk (RR) and their corresponding 95% CIs for the highest and the lowest categories of coffee intake were determined.

resultsA total of 11 observational studies (6 cross-sectional, 3 cohort and 2 case-control studies) were included in this systematic review and meta-analysis. The combined SMD suggested that there was no significant difference between the highest and the lowest coffee intake categories in terms of the SUA level (SMD=-0.09, 95% CI -0.23 to 0.05; p=0.21). Meanwhile, the overall multivariable adjusted OR for HU showed no significant difference between the highest and the lowest coffee intake categories (OR=0.84, 95% CI 0.65 to 1.09; p=0.20). However, the overall multivariable adjusted RR for gout showed a significant inverse association between coffee consumption and the incidence of gout (RR=0.43, 95% CI 0.31 to 0.59, p<0.001).

conclusionsCurrent evidences are insufficient to validate the association between coffee consumption and a lower risk of HU. Owing to the limited number of studies, the available data show that coffee consumption may be associated with a lower risk of incident gout. Further well-designed prospective researches and randomised controlled trials are therefore needed to elaborate on these issues.

Indexed as

CoffeeGoutHumansHyperuricemiaMultivariate AnalysisOdds RatioProtective FactorsCoffeeCoffeeGoutHyperuricemiaSerum uric acidSystematic review and meta-analysis

Identifiers

PMID27401353
PMCPMC4947733

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.