Evidence map›Paper›PMID 27401266›Full record

ArticleNature communications2016

Orthogonal photoswitching in a multifunctional molecular system.

Michael M Lerch, Mickel J Hansen, Willem A Velema, Wiktor Szymanski, Ben L Feringa

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
13.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 240 citations in OpenAlex.

  1. Review
  2. Article
  3. Multistate photoswitches beyond on and off.Nature communications · 2026
    Review
  4. Journal of the American Chemical Society · 2026
    Article
  5. Reversible Photoswitching of Donor-Acceptor Stenhouse Adducts in Water.Journal of the American Chemical Society · 2026
    Article
  6. A Versatile Strategy for Light-Driven Active Transport of Ions.Angewandte Chemie (International ed. in English) · 2026
    Article
  7. Article
  8. Synergistic Two-Color Photochemical Polymer Network Formation and Lithography.Angewandte Chemie (International ed. in English) · 2025
    Article
  9. Photokinetics of Mixtures of Independent Photoreactions.Molecules (Basel, Switzerland) · 2025
    Article
  10. Alternating Orthogonal Switching in a Thiophenyl-Phenyl-Bis-Azobenzene Switch.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  11. Precision Photochemistry: Every Photon Counts.Angewandte Chemie (International ed. in English) · 2025
    Article
  12. All-photonic switching of a benzo[Chemical science · 2025
    Article
  13. Article
  14. Molecular Steganography Using Multistate Photoswitchable Hydrazones.Journal of the American Chemical Society · 2025
    Article
  15. Azobenzene-Oxindole Photochromic Dyads.Angewandte Chemie (International ed. in English) · 2025
    Article
  16. Article
  17. Article
  18. Meta-Connected Oligo-Azobenzenes Outperform Their Para Counterparts.Chemphyschem : a European journal of chemical physics and physical chemistry · 2025
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Michael M LerchCentre for Systems Chemistry, Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands.
Mickel J HansenCentre for Systems Chemistry, Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands.
Willem A VelemaCentre for Systems Chemistry, Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands.
Wiktor SzymanskiCentre for Systems Chemistry, Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands.
Ben L FeringaCentre for Systems Chemistry, Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands.
University of Groningen · NLUniversity Medical Center Groningen · NL

Funding

European Research Council
6 · The paper itself

Abstract

The wavelength-selective, reversible photocontrol over various molecular processes in parallel remains an unsolved challenge. Overlapping ultraviolet-visible spectra of frequently employed photoswitches have prevented the development of orthogonally responsive systems, analogous to those that rely on wavelength-selective cleavage of photo-removable protecting groups. Here we report the orthogonal and reversible control of two distinct types of photoswitches in one solution, that is, a donor-acceptor Stenhouse adduct (DASA) and an azobenzene. The control is achieved by using three different wavelengths of irradiation and a thermal relaxation process. The reported combination tolerates a broad variety of differently substituted photoswitches. The presented system is also extended to an intramolecular combination of photoresponsive units. A model application for an intramolecular combination of switches is presented, in which the DASA component acts as a phase-transfer tag, while the azobenzene moiety independently controls the binding to α-cyclodextrin.

Identifiers

PMID27401266
PMCPMC4945879
OpenAlexW2475043505

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.