Evidence map›Paper›PMID 27400863›Full record

ArticlePsychological medicine2016

Psychological processes underlying the association between childhood trauma and psychosis in daily life: an experience sampling study.

U Reininghaus, C Gayer-Anderson, L Valmaggia, M J Kempton, M Calem, A Onyejiaka, K Hubbard, P Dazzan, S Beards, H L Fisher and 9 more

Abstract read
In one paragraph

Article in Psychological medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

U ReininghausDepartment of Psychiatry and Psychology,School for Mental Health and Neuroscience,Maastricht University,Maastricht,The Netherlands.
C Gayer-AndersonHealth Service and Population Research Department,Centre for Epidemiology and Public Health,Institute of Psychiatry, Psychology & Neuroscience, King's College London,London,UK.
L ValmaggiaPsychology Department,Institute of Psychiatry, Psychology & Neuroscience, King's College,London,UK.
M J KemptonPsychosis Studies Department,Institute of Psychiatry, Psychology & Neuroscience, King's College,London,UK.
M CalemPsychosis Studies Department,Institute of Psychiatry, Psychology & Neuroscience, King's College,London,UK.
A OnyejiakaPsychology Department,Institute of Psychiatry, Psychology & Neuroscience, King's College,London,UK.
K HubbardHealth Service and Population Research Department,Centre for Epidemiology and Public Health,Institute of Psychiatry, Psychology & Neuroscience, King's College London,London,UK.
P DazzanPsychosis Studies Department,Institute of Psychiatry, Psychology & Neuroscience, King's College,London,UK.
S BeardsHealth Service and Population Research Department,Centre for Epidemiology and Public Health,Institute of Psychiatry, Psychology & Neuroscience, King's College London,London,UK.
H L FisherMRC Social,Genetic & Developmental Psychiatry Centre,Institute of Psychiatry, Psychology & Neuroscience, King's College London,London,UK.
J G MillsPsychosis Studies Department,Institute of Psychiatry, Psychology & Neuroscience, King's College,London,UK.
P McGuirePsychosis Studies Department,Institute of Psychiatry, Psychology & Neuroscience, King's College,London,UK.
T K J CraigHealth Service and Population Research Department,Centre for Epidemiology and Public Health,Institute of Psychiatry, Psychology & Neuroscience, King's College London,London,UK.
P GaretyPsychology Department,Institute of Psychiatry, Psychology & Neuroscience, King's College,London,UK.
J van OsDepartment of Psychiatry and Psychology,School for Mental Health and Neuroscience,Maastricht University,Maastricht,The Netherlands.
R M MurrayPsychosis Studies Department,Institute of Psychiatry, Psychology & Neuroscience, King's College,London,UK.
T WykesPsychology Department,Institute of Psychiatry, Psychology & Neuroscience, King's College,London,UK.
I Myin-GermeysDepartment of Medicine,Psychiatry Research Group,Catholic University of Leuven,Leuven,Belgium.
C MorganHealth Service and Population Research Department,Centre for Epidemiology and Public Health,Institute of Psychiatry, Psychology & Neuroscience, King's College London,London,UK.

Funding

Department of Health PDF-2011-04-065Department of Health RP-PG-0606-1049EPA EP-C-13-022Medical Research Council G0600972Medical Research Council G0700995Medical Research Council G1100583Medical Research Council MR/J008915/1Medical Research Council MR/K004867/1Medical Research Council MR/K013807/1Wellcome TrustWellcome Trust WT087417
6 · The paper itself

Abstract

backgroundEvidence has accumulated that implicates childhood trauma in the aetiology of psychosis, but our understanding of the putative psychological processes and mechanisms through which childhood trauma impacts on individuals and contributes to the development of psychosis remains limited. We aimed to investigate whether stress sensitivity and threat anticipation underlie the association between childhood abuse and psychosis.

methodWe used the Experience Sampling Method to measure stress, threat anticipation, negative affect, and psychotic experiences in 50 first-episode psychosis (FEP) patients, 44 At-Risk Mental State (ARMS) participants, and 52 controls. Childhood abuse was assessed using the Childhood Trauma Questionnaire.

resultsAssociations of minor socio-environmental stress in daily life with negative affect and psychotic experiences were modified by sexual abuse and group (all p FWE < 0.05). While there was strong evidence that these associations were greater in FEP exposed to high levels of sexual abuse, and some evidence of greater associations in ARMS exposed to high levels of sexual abuse, controls exposed to high levels of sexual abuse were more resilient and reported less intense negative emotional reactions to socio-environmental stress. A similar pattern was evident for threat anticipation.

conclusionsElevated sensitivity and lack of resilience to socio-environmental stress and enhanced threat anticipation in daily life may be important psychological processes underlying the association between childhood sexual abuse and psychosis.

Indexed as

Resilience, PsychologicalAdolescentAdultAdult Survivors of Child AbuseChild Abuse, SexualEcological Momentary AssessmentFemaleHumansMaleMiddle AgedPsychotic DisordersStress, PsychologicalYoung AdultChildhood abuseecological momentary assessmentfirst-episode psychosismechanismprodromeresiliencestress sensitivitythreat anticipation

Identifiers

PMID27400863
PMCPMC5358473

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.