Evidence map›Paper›PMID 27400781›Full record

ArticleBMC infectious diseases2016

Non-malaria fevers in a high malaria endemic area of Ghana.

Kwaku Poku Asante, Seth Owusu-Agyei, Matthew Cairns, Ellen Boamah, Grace Manu, Mieks Twumasi, Richard Gyasi, George Adjei, Kingsley Kayan, Emmanuel Mahama and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Malaria Coinfections in Febrile Pediatric Inpatients: A Hospital-Based Study From Ghana.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Kwaku Poku AsanteKintampo Health Research Centre, Ghana Health Service, P. O. Box, 200, Kintampo, Brong Ahafo Region, Ghana. kwakupoku.asante@kintampo-hrc.org.
Seth Owusu-AgyeiKintampo Health Research Centre, Ghana Health Service, P. O. Box, 200, Kintampo, Brong Ahafo Region, Ghana.
Matthew CairnsLondon School of Hygiene & Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.
Ellen BoamahKintampo Health Research Centre, Ghana Health Service, P. O. Box, 200, Kintampo, Brong Ahafo Region, Ghana.
Grace ManuKintampo Health Research Centre, Ghana Health Service, P. O. Box, 200, Kintampo, Brong Ahafo Region, Ghana.
Mieks TwumasiKintampo Health Research Centre, Ghana Health Service, P. O. Box, 200, Kintampo, Brong Ahafo Region, Ghana.
Richard GyasiDepartment of Pathology, University of Ghana Medical School, College of Health, Accra, Ghana.
George AdjeiKintampo Health Research Centre, Ghana Health Service, P. O. Box, 200, Kintampo, Brong Ahafo Region, Ghana.
Kingsley KayanKintampo Health Research Centre, Ghana Health Service, P. O. Box, 200, Kintampo, Brong Ahafo Region, Ghana.
Emmanuel MahamaKintampo Health Research Centre, Ghana Health Service, P. O. Box, 200, Kintampo, Brong Ahafo Region, Ghana.
David Kwame DosooKintampo Health Research Centre, Ghana Health Service, P. O. Box, 200, Kintampo, Brong Ahafo Region, Ghana.
Kwadwo KoramNoguchi Memorial Institute for Medical Research, University of Ghana, Accra, P. O. Box LG 581, Ghana.
Brian GreenwoodLondon School of Hygiene & Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.
Daniel ChandramohanLondon School of Hygiene & Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.

Funding

Medical Research Council MR/J012394/1Medical Research Council MR/K012126/1NIAID NIH HHS HHSN266200400016C
6 · The paper itself

Abstract

backgroundThe importance of fevers not due to malaria [non-malaria fevers, NMFs] in children in sub-Saharan Africa is increasingly being recognised. We have investigated the influence of exposure-related factors and placental malaria on the risk of non-malaria fevers among children in Kintampo, an area of Ghana with high malaria transmission.

methodsBetween 2008 and 2011, a cohort of 1855 newborns was enrolled and followed for at least 12 months. Episodes of illness were detected by passive case detection. The primary analysis covered the period from birth up to 12 months of age, with an exploratory analysis of a sub-group of children followed for up to 24 months.

resultsThe incidence of all episodes of NMF in the first year of life (first and subsequent) was 1.60 per child-year (95 % CI 1.54, 1.66). The incidence of NMF was higher among infants with low birth weight [adjusted hazard ratio (aHR) 1.22 (95 % CI 1.04-1.42) p = 0.012], infants from households of poor socio-economic status [aHR 1.22 (95 % CI 1.02-1.46) p = 0.027] and infants living furthest from a health facility [aHR 1.20 (95 % CI 1.01-1.43) p = 0.037]. The incidence of all episodes of NMF was similar among infants born to mothers with or without placental malaria [aHR 0.97 (0.87, 1.08; p = 0.584)].

conclusionThe incidence of NMF in infancy is high in the study area. The incidence of NMF is associated with low birth weight and poor socioeconomic status but not with placental malaria.

Indexed as

Cause of DeathCohort StudiesFemaleFeverGhanaHealth FacilitiesHumansIncidenceInfant, Low Birth WeightInfant, NewbornMalariaMaleProportional Hazards ModelsRisk FactorsSocial ClassCohort studyFever epidemiologyGhanaMalariaNon malaria fevers

Identifiers

PMID27400781
PMCPMC4940727

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.