ArticleNature medicine2016
International AIDS Society global scientific strategy: towards an HIV cure 2016.
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Article in Nature medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 299 papers, 2 of them syntheses that pooled it.
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299citing papers in PubMed, 2 pooled it
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Who cites it
299 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Reservoir differences across HIV-1 subtypes: a systematic review to guide cure research.Frontiers in immunology · 2026Pooled it
- The Importance of Social Engagement in the Development of an HIV Cure: A Systematic Review of Stakeholder Perspectives.AIDS and behavior · 2023Pooled it
- Participant Perspectives and Experiences Following an Intensively Monitored Antiretroviral Pause in the United States: Results from the AIDS Clinical Trials Group A5345 Biomarker Study.AIDS research and human retroviruses · 2022Trial
- Effect of Intranodally Administered Dendritic Cell-Based HIV Vaccine in Combination With Pegylated Interferon α-2a on Viral Control Following ART Discontinuation: A Phase 2A Randomized Clinical Trial.Frontiers in immunology · 2021Trial
- "Cure" Versus "Clinical Remission": The Impact of a Medication Description on the Willingness of People Living with HIV to Take a Medication.AIDS and behavior · 2020Trial
- Safety and immunogenicity of Ad26 and MVA vaccines in acutely treated HIV and effect on viral rebound after antiretroviral therapy interruption.Nature medicine · 2020Trial
- Cell-associated HIV-1 RNA predicts viral rebound and disease progression after discontinuation of temporary early ART.JCI insight · 2020Trial
- The effects of antiretroviral therapy initiation time on HIV reservoir size in Chinese chronically HIV infected patients: a prospective, multi-site cohort study.BMC infectious diseases · 2019Trial
- Recent advances in molecular mechanisms to improve the efficacy of CAR-T cell therapy for viral diseases, cancer, and autoimmune diseases.Stem cell research & therapy · 2026Review
- Review
- Reactivation and Management of Endogenous Latent Herpesviruses in the Spaceflight Environment.Current microbiology · 2026Review
- Microglia cause HIV-induced transcriptional and metabolic changes in human neural organoids.Communications biology · 2026Article
- Early Combination Antiretroviral Therapy Initiation During Primary HIV Infection Restricts HIV Reservoirs and Gut-Driven Inflammation but Fails to Rewire the Systemic Cytokine Landscape.Open forum infectious diseases · 2026Article
- Review
- CRISPR Applications in HIV Management - Prevention, Diagnosis, Monitoring and Treatment.Current HIV/AIDS reports · 2026Review
- Global research landscape and trends of single-cell sequencing in sexually transmitted infections: a comprehensive bibliometric analysis from 2015 to 2025.Frontiers in reproductive health · 2026Article
- Risk of Psychiatric Morbidity in People Living With Human Immunodeficiency Virus: A Population-Based Cohort Study.Psychiatry investigation · 2026Article
- PD-1/PD-L1 blockade in HIV-associated advanced lung cancer: from mechanisms to clinical practice.Frontiers in immunology · 2026Review
- Immune checkpoint inhibitors in HIV infection: current evidence on viral reservoir regulation and immune restoration.Frontiers in immunology · 2026Review
- Searching for a HIV-1 Cure.Theranostics · 2026Review
239 more citing papers are in PubMed but not listed here.
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Authors and funding
56 authors.
Steven G DeeksDepartment of Medicine, University of California, San Francisco, San Francisco, California, USA.ORCID 0000-0001-6371-747X
Sharon R LewinThe Peter Doherty Institute for Infection and Immunity, University of Melbourne and Royal Melbourne Hospital, Melbourne, Australia.
Anna Laura RossInternational and Scientific Relations Office, ANRS, Paris, France.
Jintanat AnanworanichUS Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Monsef BenkiraneMolecular Virology Lab, Institute of Human Genetics, CNRS UPR 1142, Université de Montpellier, Montpellier, France.
Paula CannonKeck School of Medicine, University of Southern California, Los Angeles, California, USA.
Nicolas ChomontCRCHUM and Department of Microbiology, Infectiology, and Immunology, Université de Montréal, Faculty of Medicine, Montréal, Quebec, Canada.
Daniel DouekVaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Jeffrey D LifsonAIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory, Frederick, Maryland, USA.
Ying-Ru LoWorld Health Organization Regional Office for the Western Pacific, Manila, Philippines.
Daniel KuritzkesBrigham &Women's Hospital, Boston, Massachusetts, USA.
David MargolisUniversity of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, USA.ORCID 0000-0001-5714-0002
John MellorsDivision of Infectious Diseases, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Deborah PersaudJohns Hopkins University School of Medicine &Bloomberg School of Public Health, Baltimore, Maryland, USA.
Joseph D TuckerUniversity of North Carolina-Project China, Guangzhou, China.
Françoise Barre-SinoussiInstitut Pasteur, Paris, France.
International AIDS Society Towards a Cure Working Group
Galit AlterRagon Institute of MGH, MIT and Harvard, Boston, Massachusetts, USA.
Judith AuerbachDepartment of Medicine, University of California, San Francisco, San Francisco, California, USA.
Brigitte AutranSorbonne Universités, UPMC Univ Paris 06, CIMI-Paris, France.
Dan H BarouchBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Georg BehrensClinic for Immunology and Rhematology, Hannover Medical School, Hanover, Germany.
Marina CavazzanaCentre d'Investigation Clinique en biothérapie, Hôpital Necker-Enfants Malades, Paris, France.
Zhiwei ChenAIDS Institute, The University of Hong Kong, Pok Fu Lam, Hong Kong.
Éric A CohenInstitut de Recherches Cliniques de Montréal, Université de Montréal, Montréal, Quebec, Canada.
Giulio Maria CorbelliEuropean AIDS Treatment Group, Italy.
Serge EholiéProgramme PAC-CI, Centre Hospitalier Universitaire de Treichville, Abidjan, Côte d'Ivoire.
Nir EyalHarvard T. H. Chan School of Public Health, Department of Global Health and Population, Boston, Massachusetts, USA.
Sarah FidlerDepartment of Medicine, Imperial College London, London, United Kingdom.
Laurindo GarciaThe B-Change Group, Manila, Philippines.
Cynthia GrossmanNational Institute of Mental Health, NIH, Bethesda, Maryland, USA.
Gail HendersonUniversity of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, USA.
Timothy J HenrichDepartment of Medicine, University of California, San Francisco, San Francisco, California, USA.
Richard JefferysTreatment Action Group, New York, New York, USA.
Hans-Peter KiemClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Joseph McCuneDepartment of Medicine, University of California, San Francisco, San Francisco, California, USA.
Keymanthri MoodleyCentre for Medical Ethics and Law, Department of Medicine, Stellenbosch University, Western Cape, South Africa.
Peter A NewmanFactor-Inwentash Faculty of Social Work, University of Toronto, Toronto, Ontario, Canada.
Monique NijhuisDepartment of Medical Microbiology, Virology, University Medical Center Utrecht, Utrecht, Netherlands.
Moses Supercharger NsubugaJoint Clinical Research Centre, Kampala, Uganda.
Melanie OttGladstone Institutes, University of California, San Francisco, San Francisco, California, USA.
Sarah PalmerWestmead Millennium Institute for Medical Research, University of Sydney, Sydney, Australia.
Douglas RichmanVirginia San Diego Healthcare System and University of California, San Diego, San Diego, California, USA.
Asier Saez-CirionInstitut Pasteur, Paris, France.
Matthew SharpIndependent HIV Education and Advocacy Consultant, San Francisco, California, USA.
Janet SilicianoDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Guido SilvestriYerkes National Primate Research Centre, Emory University, Atlanta, Georgia, USA.
Jerome SinghNelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa.
Bruno SpireINSERM UMR_S912, Marseille, France.
Jeffrey TaylorCARE Collaboratory Community Advisory Board, Palm Springs, California, USA.
Martin TolstrupInstitute of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Susana ValenteDepartment of Immunology and Microbial Sciences, The Scripps Research Institute, Jupiter, Florida, USA.
Jan van LunzenViiV Healthcare, London, United Kingdom.
Rochelle WalenskyMassachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Ira WilsonDepartment of Health Services, Policy &Practice, Brown University School of Public Health, Providence, Rhode Island, USA.
Jerome ZackDavid Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Funding
Yerkes National Primate Research Center Role of type-I IFN in regulating COVID-19 induced inflammation and pathogenesisP51OD011132 · OD · EMORY UNIVERSITY · PI Joon Sup Lee · 2012 to 2026
$167.0MVirology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9MUjima Mentoring ProgramP30MH062246 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MALLORY O JOHNSON · 2001 to 2026
$57.4MTranslational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI CURT G BECKWITH · 1998 to 2026
$51.7MUsing NK Cells to eliminate the latent HIV reservoirU19AI096113 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MARGOLIS, DAVID M. · 2011 to 2015
$39.5MEngraftment and in vivo selection of HIV-protected stem cellsR01HL116217 · NHLBI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI KIEM, HANS-PETER · 2012 to 2017
$3.8MUnintended and Intended Implications of HIV Cure: A Social and Ethical AnalysisR01AI108366 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI RENNIE, STUART, TUCKER, JOSEPH DAVID · 2013 to 2017
$2.9MMedical Research Council MR/L00528X/1NCI NIH HHS HHSN261200800001ENHLBI NIH HHS R01 HL116217NIAID NIH HHS P30 AI042853NIAID NIH HHS P30 AI050410NIAID NIH HHS R01 AI108366NIAID NIH HHS U19 AI096113NIH HHS P51 OD011132NIMH NIH HHS P30 MH062246World Health Organization 001
Abstract
Antiretroviral therapy is not curative. Given the challenges in providing lifelong therapy to a global population of more than 35 million people living with HIV, there is intense interest in developing a cure for HIV infection. The International AIDS Society convened a group of international experts to develop a scientific strategy for research towards an HIV cure. This Perspective summarizes the group's strategy.
Indexed as
GoalsResearchAcquired Immunodeficiency SyndromeHIV InfectionsHumansInternational CooperationOrganizational ObjectivesSocieties, Medical
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.