Evidence map›Paper›PMID 27399787›Full record

ReviewAntioxidants (Basel, Switzerland)2016

Protection against Radiotherapy-Induced Toxicity.

Susan Hall, Santosh Rudrawar, Matthew Zunk, Nijole Bernaitis, Devinder Arora, Catherine M McDermott, Shailendra Anoopkumar-Dukie

Open access · goldAbstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
9.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 97 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Metallofullerenol ScAdvanced healthcare materials · 2026
    Article
  7. Validation and Derivation of miRNA-Based Germline Signatures Predicting Radiation Toxicity in Prostate Cancer.Clinical cancer research : an official journal of the American Association for Cancer Research · 2025
    Article
  8. Radiation-induced rhinosinusitis: Mechanism research and clinical progress review.World journal of otorhinolaryngology - head and neck surgery · 2024
    Review
  9. Review
  10. Review
  11. Review
  12. MicroRNAs as Regulators of Radiation-Induced Oxidative Stress.Current issues in molecular biology · 2024
    Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Susan HallMenzies Health Institute Queensland, Griffith University, Gold Coast 4222, Australia. s.hall@griffith.edu.au.
Santosh RudrawarMenzies Health Institute Queensland, Griffith University, Gold Coast 4222, Australia. s.rudrawar@griffith.edu.au.
Matthew ZunkMenzies Health Institute Queensland, Griffith University, Gold Coast 4222, Australia. m.zunk@griffith.edu.au.
Nijole BernaitisMenzies Health Institute Queensland, Griffith University, Gold Coast 4222, Australia. n.bernaitis@griffith.edu.au.
Devinder AroraMenzies Health Institute Queensland, Griffith University, Gold Coast 4222, Australia. d.arora@griffith.edu.au.
Catherine M McDermottCentre for Urology Research, Faculty of Health Sciences and Medicine, Bond University, Robina 4226, Australia. camcderm@bond.edu.au.
Shailendra Anoopkumar-DukieMenzies Health Institute Queensland, Griffith University, Gold Coast 4222, Australia. s.dukie@griffith.edu.au.
Griffith University · AUBond University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiation therapy is a highly utilized therapy in the treatment of malignancies with up to 60% of cancer patients receiving radiation therapy as a part of their treatment regimen. Radiation therapy does, however, cause a wide range of adverse effects that can be severe and cause permanent damage to the patient. In an attempt to minimize these effects, a small number of compounds have been identified and are in use clinically for the prevention and treatment of radiation associated toxicities. Furthermore, there are a number of emerging therapies being developed for use as agents that protect against radiation-induced toxicities. The aim of this review was to evaluate and summarise the evidence that exists for both the known radioprotectant agents and the agents that show promise as future radioprotectant agents.

Indexed as

inflammationoxidative stressradiotherapytoxicity

Identifiers

PMID27399787
PMCPMC5039571
OpenAlexW2469394317

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.