ArticleNutrients2016
Length Normalized Indices for Fat Mass and Fat-Free Mass in Preterm and Term Infants during the First Six Months of Life.
Article in Nutrients, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07483424 (Determination of Clinical Phenotypes of Intrauterine Growth Restriction in Term Infants Based on Body Composition. A Potential Contribution to Nutritional Management.), which is not on this map. Cited by 17 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Determination of Clinical Phenotypes of Intrauterine Growth Restriction in Term Infants Based on Body Composition. A Potential Contribution to Nutritional Management.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Body Composition of Infants Born with Intrauterine Growth Restriction: A Systematic Review and Meta-Analysis.Nutrients · 2022Pooled it
- Higher versus lower protein intake in formula-fed low birth weight infants.The Cochrane database of systematic reviews · 2020Pooled it
- The growth diversity of preterm infants at 0-36 months corrected age in China: a real-world observational study.Frontiers in pediatrics · 2025Article
- The Ratio of Body Weight/Length Squared Relates to Low Serum α-Tocopherol in Preterm Infants.Cureus · 2024Article
- Supplementing human milk for preterm infants: a nutritional challenge?Pediatric research · 2024Article
- Article
- Early weight gain trajectories and body composition in infancy in infants born very preterm.Pediatric obesity · 2021Article
- Customized Human Milk Fortification Based on Measured Human Milk Composition to Improve the Quality of Growth in Very Preterm Infants: A Mixed-Cohort Study Protocol.International journal of environmental research and public health · 2021Article
- The Revolution of Breast Milk: The Multiple Role of Human Milk Banking between Evidence and Experience-A Narrative Review.International journal of pediatrics · 2021Review
- An Observational Cohort Study and Nested Randomized Controlled Trial on Nutrition and Growth Outcomes in Moderate and Late Preterm Infants (FLAMINGO).Frontiers in nutrition · 2021Article
- Article
- Choline and choline-related nutrients in regular and preterm infant growth.European journal of nutrition · 2019Review
- Anthropometric and clinical correlates of fat mass in healthy term infants at 6 months of age.BMC pediatrics · 2019Article
- Reducing time to initiation and advancement of enteral feeding in an all-referral neonatal intensive care unit.Journal of perinatology : official journal of the California Perinatal Association · 2018Article
- Validity of Body Mass Index as a Measure of Adiposity in Infancy.The Journal of pediatrics · 2018Article
- Air displacement plethysmography (pea pod) in full-term and pre-term infants: a comprehensive review of accuracy, reproducibility, and practical challenges.Maternal health, neonatology and perinatology · 2018Review
- Body composition at birth and its relationship with neonatal anthropometric ratios: the newborn body composition study of the INTERGROWTH-21Pediatric research · 2017Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivePostnatal tissue accretion in preterm infants differs from those in utero, affecting body composition (BC) and lifelong morbidity. Length normalized BC data allows infants with different body lengths to be compared and followed longitudinally. This study aims to analyze BC of preterm and term infants during the first six months of life.
methodsThe BC data, measured using dual energy X-ray absorptiometry, of 389 preterm and 132 term infants from four longitudinal studies were combined. Fat-mass/length² (FMI) and fat-free mass/length² (FFMI) for postmenstrual age were calculated after reaching full enteral feeding, at term and two further time points up to six months corrected age.
resultsMedian FMI (preterm) increased from 0.4 kg/m² at 30 weeks to 2.5, 4.3, and 4.8 kg/m² compared to 1.7, 4.7, and 6 kg/m² in term infants at 40, 52, and 64 weeks, respectively. Median FFMI (preterm) increased from 8.5 kg/m² (30 weeks) to 11.4 kg/m² (45 weeks) and remained constant thereafter, whereas term FFMI remained constant at 11 kg/m² throughout the tested time points.
conclusionThe study provides a large dataset of length normalized BC indices. Followed longitudinally, term and preterm infants differ considerably during early infancy in the pattern of change in FMI and FFMI for age.
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