Evidence map›Paper›PMID 27399759›Full record

ArticleViruses2016

Effectiveness of Four Disinfectants against Ebola Virus on Different Materials.

Sophie Smither, Amanda Phelps, Lin Eastaugh, Sarah Ngugi, Lyn O'Brien, Andrew Dutch, Mark Stephen Lever

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Viruses, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Henipaviruses-A constant threat to livestock and humans.PLoS neglected tropical diseases · 2022
    Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Laboratory management of Crimean-Congo haemorrhagic fever virus infections: perspectives from two European networks.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2019
    Review
  17. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sophie SmitherCBR Division, Defence Science and Technology Laboratory (Dstl), Room 201, Building 7a. Dstl, Porton Down, Salisbury, Wiltshire SP4 0JQ, UK. sjsmither@dstl.gov.uk.
Amanda PhelpsCBR Division, Defence Science and Technology Laboratory (Dstl), Room 201, Building 7a. Dstl, Porton Down, Salisbury, Wiltshire SP4 0JQ, UK. alphelps@dstl.gov.uk.
Lin EastaughCBR Division, Defence Science and Technology Laboratory (Dstl), Room 201, Building 7a. Dstl, Porton Down, Salisbury, Wiltshire SP4 0JQ, UK. lseastaugh@dstl.gov.uk.
Sarah NgugiCBR Division, Defence Science and Technology Laboratory (Dstl), Room 201, Building 7a. Dstl, Porton Down, Salisbury, Wiltshire SP4 0JQ, UK. sangugi@dstl.gov.uk.
Lyn O'BrienCBR Division, Defence Science and Technology Laboratory (Dstl), Room 201, Building 7a. Dstl, Porton Down, Salisbury, Wiltshire SP4 0JQ, UK. lmobrien@dstl.gov.uk.
Andrew DutchMIG-CCHS2/C2, 1710 Naval Air Squadron, Room 104c, Unicorn House, Yeovilton BA22 8HW, UK. NAVY1710NAS-MIGCCHS2@mod.uk.
Mark Stephen LeverCBR Division, Defence Science and Technology Laboratory (Dstl), Room 201, Building 7a. Dstl, Porton Down, Salisbury, Wiltshire SP4 0JQ, UK. mslever@dstl.gov.uk.
Defence Science and Technology Laboratory · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The West Africa Ebola virus (EBOV) outbreak has highlighted the need for effective disinfectants capable of reducing viral load in a range of sample types, equipment and settings. Although chlorine-based products are widely used, they can also be damaging to equipment or apparatus that needs continuous use such as aircraft use for transportation of infected people. Two aircraft cleaning solutions were assessed alongside two common laboratory disinfectants in a contact kill assay with EBOV on two aircraft relevant materials representative of a porous and non-porous surface. A decimal log reduction of viral titre of 4 is required for a disinfectant to be deemed effective and two of the disinfectants fulfilled this criteria under the conditions tested. One product, Ardrox 6092, was found to perform similarly to sodium hypochlorite, but as it does not have the corrosive properties of sodium hypochlorite, it could be an alternative disinfectant solution to be used for decontamination of EBOV on sensitive apparatus.

Indexed as

Virus InactivationDisinfectantsEbolavirusMicrobial ViabilityViral LoadDisinfectantsdecontaminationdisinfectionEbola virusinactivationsafetysodium hypochlorite

Identifiers

PMID27399759
PMCPMC4974520
OpenAlexW2460325778

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.