ArticleMarine drugs2016
Screening of Diatom Strains and Characterization of Cyclotella cryptica as A Potential Fucoxanthin Producer.
Article in Marine drugs, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 124 citations in OpenAlex.
- Fucoxanthin Production of Microalgae under Different Culture Factors: A Systematic Review.Marine drugs · 2022Pooled it
- Development of a cost-effective medium for enhanced biomass-associated fucoxanthin and bio-silica yields of diatom (Melosira nummuloides).Journal of microbiology (Seoul, Korea) · 2026Article
- Article
- Influence of Nitrate and Light on Fucoxanthin Content and Key Gene Expression in the Marine DiatomPlants (Basel, Switzerland) · 2025Article
- Artificial Intelligence in Advancing Algal Bioactive Ingredients: Production, Characterization, and Application.Foods (Basel, Switzerland) · 2025Review
- Mixotrophic culture enhances fucoxanthin production in the haptophyte Pavlova gyrans.Applied microbiology and biotechnology · 2024Article
- Influence of light conditions on the production of chrysolaminarin using Phaeodactylum tricornutum in artificially illuminated photobioreactors.MicrobiologyOpen · 2023Article
- Effects of Temperature, Light and Salt on the Production of Fucoxanthin fromMarine drugs · 2023Article
- Valuable pigments from microalgae: phycobiliproteins, primary carotenoids, and fucoxanthin.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2023Review
- Transcriptomic and metabolomic analyses revealed regulation mechanism of mixotrophic Cylindrotheca sp. glycerol utilization and biomass promotion.Biotechnology for biofuels and bioproducts · 2023Article
- An attempt to simultaneously quantify the polysaccharide, total lipid, protein and pigment in single Cyclotella cryptica cell by Raman spectroscopy.Biotechnology for biofuels and bioproducts · 2023Article
- Microalgal cultivation characteristics using commercially available air-cushion packaging material as a photobioreactor.Scientific reports · 2023Article
- Manipulation in Culture Conditions ofMolecules (Basel, Switzerland) · 2023Article
- Two-phase microalgae cultivation for RAS water remediation and high-value biomass production.Frontiers in plant science · 2023Article
- Potential for the Production of Carotenoids of Interest in the Polar DiatomMarine drugs · 2022Article
- Fucoxanthin from Algae to Human, an Extraordinary Bioresource: Insights and Advances in up and Downstream Processes.Marine drugs · 2022Review
- Bioprospecting of Microalgae Isolated from the Adriatic Sea: Characterization of Biomass, Pigment, Lipid and Fatty Acid Composition, and Antioxidant and Antimicrobial Activity.Molecules (Basel, Switzerland) · 2022Article
- Supercritical Fluid Extraction of Fucoxanthin from the DiatomMarine drugs · 2022Article
- Optimization of fucoxanthin extraction obtained from natural by-products fromFrontiers in nutrition · 2022Article
- Effective fucoxanthin production in the flagellate algaFrontiers in bioengineering and biotechnology · 2022Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fucoxanthin has been receiving ever-increasing interest due to its broad health beneficial effects. Currently, seaweeds are the predominant source of natural fucoxanthin. However, the disappointingly low fucoxanthin content has impeded their use, driving the exploration of alternative fucoxanthin producers. In the present study, thirteen diatom strains were evaluated with respect to growth and fucoxanthin production potential. Cyclotella cryptica (CCMP 333), which grew well for fucoxanthin production under both photoautotrophic and heterotrophic growth conditions, was selected for further investigation. The supply of nitrate and light individually or in combination were all found to promote growth and fucoxanthin accumulation. When transferring heterotrophic cultures to light, fucoxanthin responded differentially to light intensities and was impaired by higher light intensity with a concomitant increase in diadinoxanthin and diatoxanthin, indicative of the modulation of Diadinoxanthin Cycle to cope with the light stress. Taken together, we, for the first time, performed the screening of diatom strains for fucoxanthin production potential and investigated in detail the effect of nutritional and environmental factors on C. cryptica growth and fucoxanthin accumulation. These results provide valuable implications into future engineering of C. cryptica culture parameters for improved fucoxanthin production and C. cryptica may emerge as a promising microalgal source of fucoxanthin.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.