Evidence map›Paper›PMID 27399651›Full record

ReviewMolecules (Basel, Switzerland)2016

Development of Droplet Microfluidics Enabling High-Throughput Single-Cell Analysis.

Na Wen, Zhan Zhao, Beiyuan Fan, Deyong Chen, Dong Men, Junbo Wang, Jian Chen

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Article
  2. Focused Liquid Pinching in Coaxial Drop Capsule Generation.Langmuir : the ACS journal of surfaces and colloids · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Research progress in isolation and identification of rumen probiotics.Frontiers in cellular and infection microbiology · 2024
    Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Na WenInstitute of Electronics, Chinese Academy of Sciences, Beijing 100190, China. wenna14@mails.ucas.ac.cn.
Zhan ZhaoInstitute of Electronics, Chinese Academy of Sciences, Beijing 100190, China. zhaozhan@mail.ie.ac.cn.
Beiyuan FanInstitute of Electronics, Chinese Academy of Sciences, Beijing 100190, China. fanbeiyuan@ucas.ac.cn.
Deyong ChenInstitute of Electronics, Chinese Academy of Sciences, Beijing 100190, China. dychen@mail.ie.ac.cn.
Dong MenWuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China. d.men@wh.iov.cn.
Junbo WangInstitute of Electronics, Chinese Academy of Sciences, Beijing 100190, China. jbwang@mail.ie.ac.cn.
Jian ChenInstitute of Electronics, Chinese Academy of Sciences, Beijing 100190, China. chenjian@mail.ie.ac.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This article reviews recent developments in droplet microfluidics enabling high-throughput single-cell analysis. Five key aspects in this field are included in this review: (1) prototype demonstration of single-cell encapsulation in microfluidic droplets; (2) technical improvements of single-cell encapsulation in microfluidic droplets; (3) microfluidic droplets enabling single-cell proteomic analysis; (4) microfluidic droplets enabling single-cell genomic analysis; and (5) integrated microfluidic droplet systems enabling single-cell screening. We examine the advantages and limitations of each technique and discuss future research opportunities by focusing on key performances of throughput, multifunctionality, and absolute quantification.

Indexed as

High-Throughput Screening AssaysMicrofluidic Analytical TechniquesAnimalsGenomicsHumansMicrofluidicsProteomicsSingle-Cell Analysisdroplet microfluidicshigh-throughputsingle-cell encapsulationsingle-cell genetic analysissingle-cell proteomic analysissingle-cell screening

Identifiers

PMID27399651
PMCPMC6272933

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.