Evidence map›Paper›PMID 27399172›Full record

ArticlePigment cell & melanoma research2016

Double Trouble: Kinase domain duplication as a new path to drug resistance.

Hsin-Yi Chen, Donita C Brady, Jessie Villanueva

Abstract readNewsComment
In one paragraph

Article in Pigment cell & melanoma research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Hsin-Yi Chen
Donita C Brady
Jessie Villanuevajvillanueva@wistar.org.

Funding

Tumor Microenvironment and MetastasisP30CA010815 · NCI · WISTAR INSTITUTE · PI Luis J Montaner · 1985 to 2026
$75.9M
Targeting the MAP and PI3 Kinase Pathways in MelanomaP01CA114046 · NCI · WISTAR INSTITUTE · PI HERLYN, MEENHARD F, WEERARATNA, ASHANI T · 2008 to 2023
$37.1M
Molecular approaches to overcome intrinsic drug resistance in BRAF and NRAS-mutanK01CA175269 · NCI · WISTAR INSTITUTE · PI VILLANUEVA, JESSIE · 2013 to 2017
$754k
Copper reduction as a novel therapy in BRAF-mutant positive cancersK01CA178145 · NCI · UNIVERSITY OF PENNSYLVANIA · PI BRADY, DONITA C · 2013 to 2015
$274k
NCI NIH HHS K01 CA175269NCI NIH HHS K01 CA178145NCI NIH HHS P01 CA114046NCI NIH HHS P30 CA010815
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Drug ResistanceDrug Resistance, Neoplasm

Identifiers

PMID27399172
PMCPMC5223244

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.