ArticleMedicine2016
Impact of demographic, genetic, and bioimpedance factors on gestational weight gain and birth weight in a Romanian population: A cross-sectional study in mothers and their newborns: the Monebo study (STROBE-compliant article).
Article in Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic Review ofInternational journal of molecular sciences · 2024Pooled it
- Trial
- VaginalJournal of clinical medicine · 2026Article
- Association of sleep variability and irregularity with gestational metabolic syndrome: a birth cohort study.Frontiers in endocrinology · 2026Article
- Prebiotics, Probiotics, and Synbiotics-A Research Hotspot for Pediatric Obesity.Microorganisms · 2023Review
- Relationship between birth weight and ambient temperature during pregnancy in a cross-sectional study of the residents of Suzhou, China.Frontiers in public health · 2023Article
- Article
- Relationships between excessive gestational weight gain and energy and macronutrient intake in pregnant women.The Journal of international medical research · 2020Article
- Article
- MC4R and ENPP1 gene polymorphisms and their implication in maternal and neonatal risk for obesity.Scientific reports · 2019Article
- The usefulness of inflammatory biomarkers in diagnosing child and adolescent's gastritis: STROBE compliant article.Medicine · 2019Article
- The relationship between MMP9 and ADRA2A gene polymorphisms and mothers-newborns' nutritional status: an exploratory path model (STROBE compliant article).Pediatric research · 2019Article
- An uncommon case of herpetic esophagitis in a small child with allergic rhinitis: A case report and literature review (CARE compliant).Medicine · 2019Article
- Early Inflammatory Status Related to Pediatric Obesity.Frontiers in pediatrics · 2019Article
- An Exploration of the Determinants of Gestational Weight Gain in African American Women: Genetic Factors and Energy Expenditure.Biological research for nursing · 2018Observational
- Association of interleukin-6 polymorphisms with obesity or metabolic traits in young Mexican-Americans.Obesity science & practice · 2018Article
- New Insights Regarding Genetic Aspects of Childhood Obesity: A Minireview.Frontiers in pediatrics · 2018Review
- Article
- Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study had 2 objectives, first, to investigate possible relationships between increased gestational weight gain and demographic, clinical, paraclinical, genetic, and bioimpedance (BIA) characteristics of Romanian mothers, and second, to identify the influence of predictors (maternal and newborns characteristics) on our outcome birth weight (BW).We performed a cross-sectional study on 309 mothers and 309 newborns from Romania, divided into 2 groups: Group I-141 mothers with high gestational weight gain (GWG) and Group II-168 mothers with normal GWG, that is, control group.The groups were evaluated regarding demographic, anthropometric (body mass index [BMI], middle upper arm circumference, tricipital skinfold thickness, weight, height [H]), clinical, paraclinical, genetic (interleukin 6 [IL-6]: IL-6 -174G>C and IL-6 -572C>G gene polymorphisms), and BIA parameters.We noticed that fat mass (FM), muscle mass (MM), bone mass (BM), total body water (TBW), basal metabolism rate (BMR) and metabolic age (P < 0.001), anthropometric parameters (middle upper arm circumference, tricipital skinfold thickness; P < 0.001/P = 0.001) and hypertension (odds ratio = 4.65, 95% confidence interval: 1.27-17.03) were higher in mothers with high GWG. BW was positively correlated with mothers' FM (P < 0.001), TBW (P = 0.001), BMR (P = 0.02), while smoking was negatively correlated with BW (P = 0.04). Variant genotype (GG+GC) of the IL-6 -572C>G polymorphism was higher in the control group (P = 0.042).We observed that high GWG may be an important predictor factor for the afterward BW, being positively correlated with FM, TBW, BMR, metabolic age of the mothers, and negatively with the mother's smoking status. Variant genotype (GG+GC) of the IL-6 -572C>G gene polymorphism is a protector factor against obesity in mothers. All the variables considered explained 14.50% of the outcome variance.
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