ArticleMedicine2016
Acute fibrinous and organizing pneumonia: A report of 13 cases in a tertiary university hospital.
Article in Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- Acute Fibrinous and Organizing Pneumonia Versus Organizing Pneumonia: A Comparative Study of Clinical, Radiological, Histological, and Immunophenotypic Features.Journal of clinical medicine · 2026Article
- Acute fibrinous and organising pneumonia (AFOP): a case series highlighting diverse aetiologies and clinical outcomes in three patients.European clinical respiratory journal · 2026Article
- Korean Guidelines for Diagnosis and Management of Interstitial Lung Disease: Cryptogenic Organizing Pneumonia.Tuberculosis and respiratory diseases · 2025Article
- Clinicopathologic Features of Isolated AFOP Nodules Radiologically Mimicking Malignancy in Post COVID-19 Patients: A Case Series Study.Journal of clinical medicine · 2025Article
- Acute fibrinous and organising pneumonia presenting with mass-like imaging: a case report.Diagnostic pathology · 2025Article
- Everolimus Induced Acute Fibrinous and Organizing Pneumonia (AFOP): A Rare Case Report.Case reports in pulmonology · 2025Article
- Acute fibrinous and organizing pneumonia after lung transplantation: A case report of treatment with infliximab and tocilizumab and literature review.Respiratory medicine case reports · 2025Article
- Prognostic Impact of Aetiology in Adult Hemophagocytic Lymphohistiocytosis: Insights from an Intensive Care Unit Experience.European journal of case reports in internal medicine · 2024Article
- Acute fibrinous and organizing pneumonia associated with Candida: A case report.Respiratory medicine case reports · 2024Article
- Article
- Lesson of urgent bilateral lobar lung transplantation for acute fibrinous and organizing pneumonia: a case report.AME case reports · 2023Article
- Update on cryptogenic organizing pneumonia.Frontiers in medicine · 2023Review
- Two methods of lung biopsy for histological confirmation of acute fibrinous and organizing pneumonia: A case report.World journal of clinical cases · 2022Article
- Clinical features and long-term prognosis of acute fibrinous and organizing pneumonia histologically confirmed by surgical lung biopsy.BMC pulmonary medicine · 2022Article
- Case report: Corticosteroid-resistant acute fibrinous and organizing pneumonia with myelodysplastic syndrome.Frontiers in medicine · 2022Article
- Acute lung injury-from cannabis to COVID.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2022Review
- Acute fibrinous and organizing pneumonia complicated with hemophagocytic lymphohistiocytosis caused by chronic active Epstein-Barr virus infection: a case report.BMC infectious diseases · 2021Article
- sFlt-1 and CA 15.3 are indicators of endothelial damage and pulmonary fibrosis in SARS-CoV-2 infection.Scientific reports · 2021Article
- Acute fibrinous and organizing pneumonia following hemophagocytic syndrome in two adult patients with hematological malignancies.Journal of clinical and experimental hematopathology : JCEH · 2021Article
- Chest-CT mimics of COVID-19 pneumonia-a review article.Emergency radiology · 2021Review
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAcute fibrinous and organizing pneumonia (AFOP) is a rare diffuse pulmonary disease, but it is not yet known whether it is a distinct form of interstitial pneumonia or simply a reflection of a tissue sampling issue.
methodsCross-sectional evaluation of clinical and radiological findings, treatments, and outcomes for patients with histologically confirmed AFOP at a tertiary university hospital between 2002 and 2015.
resultsThirteen patients (7 women, 53.8%) with a mean ± SD age of 53.5 ± 16.1 years were included. The main symptoms were fever (69.2%), cough (46.2%), and chest pain (30.8%). All patients presented a radiological pattern of consolidation and 5 (38.5%) had simultaneous ground-glass areas. Histology was obtained by computed tomography-guided transthoracic biopsy in 61.5% of cases and by surgical lung biopsy in the remaining cases. Several potential etiologic factors were identified. Eight patients (61.5%) had hematologic disorders and 3 had undergone an autologous hematopoietic cell transplant. Two (15.4%) had microbiologic isolates, 5 (38.4%) had drug-induced lung toxicity, and 2 (15.4%) were classified as having idiopathic AFOP. In addition to antibiotics and diuretics used to treat the underlying disease, the main treatment was corticosteroids, combined in some cases with immunosuppressants. Median survival was 78 months and 6 patients (46.2%) were still alive at the time of analysis.
conclusionOur findings for this series of patients confirm that AFOP is a nonspecific reaction to various agents with a heterogeneous clinical presentation and clinical course that seems to be influenced mainly by the severity of the underlying disorder.
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