Evidence map›Paper›PMID 27399073›Full record

SynthesisMedicine2016

Long-term clinical outcomes of laparoscopy-assisted distal gastrectomy versus open distal gastrectomy for early gastric cancer: A comprehensive systematic review and meta-analysis of randomized control trials.

Wei Lu, Jian Gao, Jingyun Yang, Yijian Zhang, Wenjie Lv, Jiasheng Mu, Ping Dong, Yingbin Liu

Abstract readComparative StudyMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Early Gastric Cancer: Update on Prevention, Diagnosis and Treatment.International journal of environmental research and public health · 2023
    Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Risk factors for 30-day hospital readmission after radical gastrectomy: a single-center retrospective study.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2019
    Article
  12. Article
  13. Article
  14. Article
  15. Minimally invasive surgery for gastric gastrointestinal stromal tumors.Translational gastroenterology and hepatology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wei LuDepartment of General Surgery and Laboratory of General Surgery, Xinhua Hospital, Affiliated to Shanghai Jiao Tong University, School of Medicine Institute of Biliary Tract Diseases Research, Shanghai Jiao Tong University School of Medicine Department of Nutrition, Zhongshan hospital, Affiliated to Fudan University Center of Clinical Epidemiology and Evidence-based Medicine, Fudan University, Shanghai, China Rush Alzheimer's Disease Center Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.
Jian Gao
Jingyun Yang
Yijian Zhang
Wenjie Lv
Jiasheng Mu
Ping Dong
Yingbin Liu

Funding

Exploring the Role of the Brain Epigenome: Cognitive Decline and Life ExperiencesR01AG036042 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BENNETT, DAVID ALAN · 2009 to 2013
$4.1M
NIA NIH HHS R01 AG036042
6 · The paper itself

Abstract

The objective of this study was to compare long-term surgical outcomes and complications of laparoscopy-assisted distal gastrectomy (LADG) with open distal gastrectomy (ODG) for the treatment of early gastric cancer (EGC) based on a review of available randomized controlled trials (RCTs) evaluated using the Cochrane methodology.RCTs comparing LADG and ODG were identified by a systematic literature search in PubMed, Cochrane Library, MEDLINE, EMBASE, Scopus, and the China Knowledge Resource Integrated Database, for papers published from January 1, 2003 to July 30, 2015. Meta-analyses were performed to compare the long-term clinical outcomes.Our systematic literature search identified 8 eligible RCTs including 732 patients (374 LADGs and 358 ODGs), with low overall risk of bias. Long-term mortality and relapse rate were comparable for both techniques. The long-term complication rate was 8.47% in LADG groups and 13.62% in the ODG group, indicating that LADG was associated with lower risk for long-term complications (RR = 0.63; 95%CI = 0.39-1.00; P = 0.03).In the treatment of EGC, LADG lowered the rate of long- and short-term complications and promoted earlier recovery, with comparable oncological outcomes to ODG.

Indexed as

LaparoscopyGastrectomyGastroenterostomyHumansNeoplasm StagingRandomized Controlled Trials as TopicStomach NeoplasmsTime FactorsTreatment Outcome

Identifiers

PMID27399073
PMCPMC5058802

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.