Evidence map›Paper›PMID 27398881›Full record

ReviewPsychoneuroendocrinology2016

The effect of self-reported health on latent herpesvirus reactivation and inflammation in an ethnically diverse sample.

Kyle W Murdock, Christopher P Fagundes, M Kristen Peek, Vansh Vohra, Raymond P Stowe

Open access · greenAbstract readReview
In one paragraph

Review in Psychoneuroendocrinology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Self-rated health and inflammation: Associations among partnered sexual minority and heterosexual adults.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026
    Article
  3. Article
  4. Sex differences in executive functioning and latent herpesvirus reactivation among bereaved and nonbereaved individuals.Stress and health : journal of the International Society for the Investigation of Stress · 2019
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Kyle W MurdockDepartment of Psychology, Rice University, 6500 Main Street, Houston, TX 77005, USA.
Christopher P FagundesDepartment of Psychology, Rice University, 6500 Main Street, Houston, TX 77005, USA; Department of Symptom Research, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 1450, Houston, TX 77030, USA; Department of Psychiatry, Baylor College of Medicine, One Baylor Plaza - BCM350, Houston, TX 77030, USA. Electronic address: christopher.fagundes@rice.edu.
M Kristen PeekDepartment of Preventative Medicine and Community Health, The University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555, USA.
Vansh VohraDepartment of Psychology, Rice University, 6500 Main Street, Houston, TX 77005, USA.
Raymond P StoweMicrogen Laboratories, 903 Texas Avenue, La Marque, TX 77568, USA.
Rice University · USMicrogen (United States) · USThe University of Texas Medical Branch at Galveston · US

Funding

UTMB Center for Population Health and Health DisparitiesP50CA105631 · NCI · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI GOODWIN, MD, JAMES S. · 2003 to 2008
$8.5M
Project Heart: Biobehavioral Effects on Cardiovascular Risk for Bereaved SpousesR01HL127260 · NHLBI · RICE UNIVERSITY · PI FAGUNDES, CHRISTOPHER PAUL · 2015 to 2019
$4.1M
NCI NIH HHS P50 CA105631NHLBI NIH HHS R01 HL127260
6 · The paper itself

Abstract

Self-rated health (SRH) is a reliable predictor of health outcomes including morbidity and mortality. Immune dysregulation is one hypothesized mechanism underlying the association between SRH and health outcomes. Indeed, poorer SRH is associated with greater inflammation. The association between SRH and reactivation of latent herpesviruses is unknown, representing an important gap in the literature given that reactivation of latent herpesviruses leads to enhanced inflammation. The present study addressed this important gap in the literature by examining associations between SRH, inflammation (i.e., peripheral cytokines in the blood), and reactivation of latent herpesviruses among a sample of 1208 individuals participating in the Texas City Stress and Health Study. Participants completed a self-report measure of SRH and a blood draw. Results indicated that higher SRH was associated with lower reactivation of latent herpesviruses and inflammation. Moreover, reactivation of latent herpesviruses partially mediated the association between SRH and inflammation. Accordingly, findings add to our growing understanding of the association between SRH and immune dysfunction.

Indexed as

Health StatusAdultCross-Sectional StudiesCytomegalovirus InfectionsDiagnostic Self EvaluationEpstein-Barr Virus InfectionsFemaleHerpes SimplexHumansInflammationMaleMiddle AgedTexasCytomegalovirusEpstein-Barr virusInflammationSelf-rated health

Identifiers

PMID27398881
PMCPMC5116910
OpenAlexW2466356149

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.