Evidence map›Paper›PMID 27398730›Full record

ArticleThe American journal of drug and alcohol abuse2016

Increased self-reported impulsivity in methamphetamine users maintaining drug abstinence.

Hannah W Jones, Andy C Dean, Kimberly A Price, Edythe D London

Abstract read
In one paragraph

Article in The American journal of drug and alcohol abuse, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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  14. Tactile Discrimination, Praxis and Cognitive Impulsivity in ADHD Children: A Cross-Sectional Study.International journal of environmental research and public health · 2020
    Article
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  17. Review
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  19. An electroencephalography connectome predictive model of craving for methamphetamine.International journal of clinical and health psychology : IJCHP
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hannah W Jonesa Department of Clinical Psychology, Fuller Graduate School of Psychology, Fuller Theological Seminary , Pasadena , CA , USA.
Andy C Deanb Department of Psychiatry and Biobehavioral Sciences , UCLA Semel Institute for Neuroscience , Los Angeles , CA , USA.
Kimberly A Priceb Department of Psychiatry and Biobehavioral Sciences , UCLA Semel Institute for Neuroscience , Los Angeles , CA , USA.
Edythe D Londonb Department of Psychiatry and Biobehavioral Sciences , UCLA Semel Institute for Neuroscience , Los Angeles , CA , USA.

Funding

UCLA Clinical and Translational Science InstituteUL1TR000124 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2012 to 2015
$57.0M
NEUROCHEMISTRY OF MODAFINIL-MA INTERACTION IN RAT BRAINP20DA022539 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LONDON, EDYTHE DANICK · 2006 to 2009
$2.9M
Neural Systems, Inhibitory Control, and Methamphetamine DependenceR01DA020726 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LONDON, EDYTHE DANICK · 2005 to 2008
$2.0M
Neurobehavioral Predictors of Cognitive Decline in Methamphetamine DependenceK23DA027734 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DEAN, ANDREW CLARK · 2010 to 2014
$842k
CYP2D6, brain structure, and cognitive function in methamphetamine dependenceR21DA034928 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DEAN, ANDREW CLARK · 2013 to 2014
$424k
NCATS NIH HHS UL1 TR000124NIDA NIH HHS K23 DA027734NIDA NIH HHS P20 DA022539NIDA NIH HHS R01 DA020726NIDA NIH HHS R21 DA034928
6 · The paper itself

Abstract

backgroundImpulsivity has been proposed as an important factor in the initiation and maintenance of addiction. Indirect evidence suggests that some methamphetamine users report less impulsivity when they are using methamphetamine compared to when abstaining from drug use, but this hypothesis has not been directly tested. OBJECTIVES/

methodsIn this study, self-reports of impulsivity were obtained from 32 methamphetamine-dependent (DSM-IV) research participants and 41 healthy control subjects, using the Barratt Impulsiveness Scale-11. The methamphetamine users were assessed during an active period of methamphetamine use, as determined through urinalysis, and again after approximately 1 week of confirmed abstinence. Control subjects likewise completed two assessments. A subset of participants also completed serial assessments of the Beck Depression Inventory (Methamphetamine Group, N = 17, Control Group, N = 38) and the Methamphetamine Withdrawal Questionnaire (Methamphetamine Group, N = 12).

resultsThere was a significant interaction of group with time on impulsivity (p = 0.044), reflecting a significant increase from the first to the second assessment in the methamphetamine users (p = 0.013), but no change among healthy control subjects. In contrast, depressive and withdrawal symptoms significantly decreased between the first and second assessments in the methamphetamine users (ps ≤0.01). Change in impulsivity in methamphetamine users was not significantly correlated with change in withdrawal or depression (ps >0.05).

conclusionsThese findings suggest that methamphetamine users report more impulsivity when abstaining from drug use, an effect that is not significantly related to methamphetamine withdrawal. Attenuation of impulsivity may reinforce continued methamphetamine use in these individuals.

Indexed as

Self ReportAdultAmphetamine-Related DisordersCase-Control StudiesDepressionFemaleHumansImpulsive BehaviorMaleMethamphetamineSubstance Withdrawal SyndromeYoung AdultMethamphetamineabstinenceDrug abuseimpulsivitymethamphetamineself-medicationstimulantwithdrawal

Identifiers

PMID27398730
PMCPMC5055455

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.